Home / PLSCR1 Knockout Cell Lines

PLSCR1 Knockout Cell Lines

Gene: PLSCR1

Official Full Name: phospholipid scramblase 1provided by HGNC

Gene Summary: This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses. [provided by RefSeq, May 2022]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01459 PLSCR1 Knockout cell line(A549) Human PLSCR1 1:3~1:4 Negative Online Inquiry
KO15024 PLSCR1 Knockout cell line (HeLa) Human PLSCR1 1:3~1:6 Negative Online Inquiry
KO15025 PLSCR1 Knockout cell line (HCT 116) Human PLSCR1 1:2~1:4 Negative Online Inquiry
KO15026 PLSCR1 Knockout cell line (HEK293) Human PLSCR1 1:3~1:6 Negative Online Inquiry

Background

PLSCR1 Gene Knockout Cell Lines represent a groundbreaking innovation in molecular biology, specifically designed to facilitate the study of biological processes related to the phospholipid scramblase 1 (PLSCR1) protein. This product features genetically modified cell lines in which the PLSCR1 gene has been effectively knocked out, enabling researchers to investigate the functional consequences of PLSCR1 deficiency in both cellular and systemic contexts.

The primary mechanism at play involves the disruption of the endogenous PLSCR1 gene through precise CRISPR-Cas9 gene editing technology. This leads to a complete lack of PLSCR1 protein, which is crucial for regulating phospholipid asymmetry during cellular events such as apoptosis, platelet activation, and immune response. By employing these knockout cell lines, researchers can delve deeper into the signaling pathways and physiological processes impacted by PLSCR1, leading to significant discoveries in fields like immunology, cancer research, and cardiovascular studies.

The scientific importance of PLSCR1 Knockout Cell Lines lies in their application for elucidating the multifaceted roles of PLSCR1 in disease models, offering insights into how its absence may lead to altered cellular behavior and contribute to pathophysiology. This product stands apart from alternatives by providing a versatile, reliable model that ensures reproducibility and precision in experimental design, significantly enriching the depth of research possibilities.

Additionally, PLSCR1 Gene Knockout Cell Lines are invaluable tools for both academic and commercial laboratories seeking to advance their understanding of cell biology in health and disease. The potential for high-impact research applications paired with the reliability and cost-effectiveness of these cell lines makes them a compelling choice for researchers looking to explore new frontiers in scientific investigation.

Our company specializes in the development of advanced genetic tools and cell models, ensuring that you receive high-quality products backed by rigorous validation. With our expertise, we aim to empower researchers and clinicians alike in their quest for scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.