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PLPP7 Knockout Cell Lines

Gene: PLPP7

Official Full Name: phospholipid phosphatase 7 (inactive)provided by HGNC

Gene Summary: Predicted to enable sphingosine-1-phosphate phosphatase activity. Predicted to act upstream of or within negative regulation of myotube differentiation. Predicted to be located in endoplasmic reticulum membrane and nucleus. Predicted to be active in membrane and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24620 PLPP7 Knockout cell line (HEK293) Human PLPP7 1:3~1:6 Negative Online Inquiry

Background

PLPP7 Gene Knockout Cell Lines are genetically modified cell lines designed to provide researchers with vital tools for studying the PLPP7 (Phospholipid Phosphatase 7) gene function and its role in cellular processes. These cell lines are created through precise genetic engineering techniques, resulting in a complete knockout of the PLPP7 gene, thus enabling the investigation of gene function by eliminating its expression.

The primary function of PLPP7 Gene Knockout Cell Lines is to serve as a model for examining the physiological and pathological effects of PLPP7 deficiency. By utilizing these cell lines, researchers can explore the biochemical pathways influenced by PLPP7, including lipid metabolism and signaling pathways. The knockout mechanism allows for significant insights into how the absence of PLPP7 impacts cellular behavior, offering a clearer understanding of its contributions to diseases such as cancer, cardiovascular disorders, and metabolic syndromes.

The scientific significance of these cell lines extends into several research and clinical applications. They provide a platform for drug discovery, allowing for the investigation of new therapeutic targets in conditions where PLPP7 is implicated. Moreover, these knockout models facilitate the validation of gene function in various biological assays, making them invaluable for translational research that seeks to bridge laboratory findings to clinical applications.

Compared to alternatives like short hairpin RNA (shRNA) silencing or CRISPR-based knockdowns that may have off-target effects, PLPP7 Gene Knockout Cell Lines offer a stable and complete gene knockout, thus ensuring higher specificity and reliability in experimental outcomes. Researchers benefit from their ability to generate consistent data across multiple experiments, thus enhancing reproducibility.

In the competitive landscape of gene-editing tools, PLPP7 Gene Knockout Cell Lines stand out for their precision and applicability in a variety of biological contexts. The reliability of these models provides researchers and clinicians with the confidence to draw meaningful conclusions from their studies, ultimately propelling the advancement of our understanding of gene function in health and disease.

As a company dedicated to advancing biological research, we leverage our expertise in genetic engineering and cell line development to offer innovative solutions like the PLPP7 Gene Knockout Cell Lines. Our commitment to quality ensures that researchers have access to the best resources for their important work in advancing the frontiers of science.

Please note that all services are for research use only. Not intended for any clinical use.

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