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PLGRKT Knockout Cell Lines

Gene: PLGRKT

Official Full Name: plasminogen receptor with a C-terminal lysineprovided by HGNC

Gene Summary: Predicted to be involved in positive regulation of plasminogen activation. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15033 PLGRKT Knockout cell line (HeLa) Human PLGRKT 1:3~1:6 Negative Online Inquiry
KO15034 PLGRKT Knockout cell line (HCT 116) Human PLGRKT 1:2~1:4 Negative Online Inquiry
KO15035 PLGRKT Knockout cell line (HEK293) Human PLGRKT 1:3~1:6 Negative Online Inquiry
KO15036 PLGRKT Knockout cell line (A549) Human PLGRKT 1:3~1:4 Negative Online Inquiry

Background

PLGRKT Gene Knockout Cell Lines are highly specialized and engineered cellular models designed to facilitate the functional analysis of the PLGRKT gene, known to play a critical role in various biological pathways, including cancer progression and immune response modulation. These cell lines are produced through advanced CRISPR/Cas9 gene-editing technology, which enables precise disruption of the target gene, providing researchers with invaluable tools for studying gene function, pathogenic mechanisms, and potential therapeutic targets.

The primary function of the PLGRKT Gene Knockout Cell Lines lies in their ability to help elucidate the biological roles of the PLGRKT gene in vitro. By comparing normal cellular functions with those in knockout models, researchers can observe phenotypic changes, evaluate signaling pathways, and assess the implications for cellular behavior, such as proliferation, apoptosis, and migration. This mechanistic insight is crucial for advancing our understanding of diseases linked to the PLGRKT gene, particularly in oncology and immunology.

The scientific importance of these cell lines extends beyond basic research to clinical applications, including drug discovery and development. Pharmaceutical companies and academic institutions can utilize PLGRKT Gene Knockout Cell Lines to screen for novel therapeutic compounds that target the associated pathways. Moreover, the incorporation of these models into research can accelerate the preclinical validation process, enhancing the translational potential of findings into clinical practice.

What sets PLGRKT Gene Knockout Cell Lines apart from other gene-editing models is their high specificity and reproducibility, thanks to rigorous validation protocols that ensure the complete knockout of the target gene without off-target effects. This level of precision minimizes experimental variability and maximizes the reliability of research outcomes, making these cell lines a superior choice for discerning the nuanced roles of the PLGRKT gene.

For researchers and clinicians focused on cutting-edge genetic research or translational medicine, PLGRKT Gene Knockout Cell Lines represent a significant resource that can streamline experimental design and yield impactful data. By leveraging our extensive expertise in genetic engineering and cell line development, we are committed to providing high-quality biological products that empower scientific discovery and medical advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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