Gene: PLEKHG6
Official Full Name: pleckstrin homology and RhoGEF domain containing G6provided by HGNC
Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Located in cell junction and centrosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15049 | PLEKHG6 Knockout cell line (HCT 116) | Human | PLEKHG6 | 1:2~1:4 | Negative | Online Inquiry |
KO15050 | PLEKHG6 Knockout cell line (A549) | Human | PLEKHG6 | 1:3~1:4 | Negative | Online Inquiry |
PLEKHG6 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functional effects of the PLEKHG6 gene, which encodes a protein involved in cytoskeletal organization and cellular signaling pathways. These knockout cell lines are invaluable tools for elucidating the biological role of PLEKHG6 in various cellular processes, particularly those relating to development, migration, and differentiation.
The key function of these knockout cell lines lies in their ability to facilitate precise examinations of the PLEKHG6 gene's contributions to cell behavior. By employing CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete disruption of the PLEKHG6 gene, allowing researchers to investigate the resultant phenotypic changes. This enables a clearer understanding of downstream signaling cascades and potential therapeutic targets associated with diseases such as cancer and neurological disorders, emphasizing their relevance in both fundamental research and applied clinical studies.
The scientific importance of PLEKHG6 Gene Knockout Cell Lines extends into numerous research and clinical settings. They are instrumental in drug discovery processes, functional genomics, and the development of gene therapies. Additionally, they contribute to the advancement of personalized medicine by enabling the characterization of individual patient cellular responses to therapies.
What sets our PLEKHG6 Gene Knockout Cell Lines apart from alternative models is their high specificity, reproducibility, and the meticulous validation of functional loss. Additionally, our extensive technical support and chemogenomic insights provide researchers with a comprehensive understanding of gene interactions within a cellular context, enhancing the interpretability of experimental results.
Ultimately, these products are essential for researchers and clinicians seeking to unravel complex biological questions and address unmet medical needs. Our company's long-standing expertise in genetic engineering and commitment to quality research tools ensure that you receive reliable, cutting-edge products tailored to advance scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
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