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PLEKHA2 Knockout Cell Lines

Gene: PLEKHA2

Official Full Name: pleckstrin homology domain containing A2provided by HGNC

Gene Summary: Enables fibronectin binding activity; laminin binding activity; and phosphatidylinositol-3,4-bisphosphate binding activity. Involved in positive regulation of cell-matrix adhesion. Located in cytoplasm and membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15083 PLEKHA2 Knockout cell line (HeLa) Human PLEKHA2 1:3~1:6 Negative Online Inquiry
KO15084 PLEKHA2 Knockout cell line (HCT 116) Human PLEKHA2 1:2~1:4 Negative Online Inquiry
KO15085 PLEKHA2 Knockout cell line (HEK293) Human PLEKHA2 1:3~1:6 Negative Online Inquiry
KO15086 PLEKHA2 Knockout cell line (A549) Human PLEKHA2 1:3~1:4 Negative Online Inquiry

Background

PLEKHA2 Gene Knockout Cell Lines are sophisticated biological research tools designed for investigating the role of the PLEKHA2 gene in various cellular processes. These cell lines have been meticulously created using CRISPR-Cas9 gene editing technology to induce targeted deletions in the PLEKHA2 gene. This gene encodes a protein that plays a critical role in several signaling pathways and cellular interactions, making gene knockout models invaluable for elucidating the molecular mechanisms underlying various biological functions and diseases.

The primary function of the PLEKHA2 Gene Knockout Cell Lines is to provide researchers with precise models that allow for the investigation of gene function, regulation, and the impact of the absence of PLEKHA2 on cellular behaviors. By utilizing these knockout cell lines, scientists can study alterations in cellular proliferation, migration, and response to stimuli, as well as dissect the pathway interactions that may lead to disease phenotypes.

From a scientific perspective, the PLEKHA2 Gene Knockout Cell Lines are fundamental for advancing research related to cancer biology, neurodegenerative diseases, and other disorders where PLEKHA2 involvement is suspected. They serve as powerful platforms for drug discovery and therapeutic intervention studies, enabling the identification of potential targets for drug action and the validation of novel therapeutic strategies.

One of the key advantages of our PLEKHA2 Gene Knockout Cell Lines is the precision and reliability of the CRISPR-Cas9 technology employed in their development, which minimizes off-target effects and enhances reproducibility compared to traditional knockout methods. Additionally, these cell lines are readily available and easy to integrate into various experimental setups, which significantly expedites research timelines.

Our product is invaluable for researchers and clinicians looking to deepen their understanding of gene function and its implications in health and disease. By employing these knockout models, they can accelerate their discoveries and drive innovation in the fields of genetics and cell biology.

With a commitment to providing high-quality biological products and cutting-edge research tools, our company harnesses extensive expertise in genomics and cell biology to support scientific advancement. The PLEKHA2 Gene Knockout Cell Lines represent a significant addition to our product portfolio, reflecting our dedication to enhancing research capabilities across various disciplines.

Please note that all services are for research use only. Not intended for any clinical use.

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