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PLD5 Knockout Cell Lines

Gene: PLD5

Official Full Name: phospholipase D family member 5provided by HGNC

Gene Summary: Predicted to enable catalytic activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38327 PLD5 Knockout cell line (A549) Human PLD5 1:3~1:4 Negative Online Inquiry

Background

PLD5 Gene Knockout Cell Lines are meticulously engineered biological tools designed to facilitate in-depth research on phospholipase D5 (PLD5), a critical enzyme implicated in various cellular processes, including membrane fusion, signal transduction, and metabolic regulation. These cell lines have been generated through advanced CRISPR-Cas9 gene editing technology, effectively disrupting the PLD5 gene and allowing for the comprehensive study of its physiological and pathological roles in both in vitro and in vivo systems.

The primary function of PLD5 Gene Knockout Cell Lines revolves around their ability to serve as a model for understanding the implications of absent PLD5 activity. Scientists can examine cellular responses to stimuli, investigate alterations in metabolic pathways, and elucidate mechanisms of disease progression, particularly in cancer and cardiovascular diseases where PLD5 has been demonstrated to play a significant role. By providing a controlled environment devoid of the PLD5 gene, these knockout cell lines enable researchers to decipher the consequences of its absence and identify potential compensatory mechanisms employed by the cell.

The scientific importance of PLD5 Gene Knockout Cell Lines extends into both academic and clinical research settings, making them invaluable for drug discovery and therapeutic development. Their unique ability to model physiological conditions enhances researchers' capacity to identify novel targets for intervention and to evaluate the efficacy of pharmaceutical compounds aimed at modulating PLD5-associated pathways.

What sets PLD5 Gene Knockout Cell Lines apart from traditional models is their high specificity and reliability. Unlike conventional experimental approaches, which may yield ambiguous results due to the presence of functional PLD5, these knockout lines provide unequivocal insights by eliminating confounding variables. Additionally, they offer reproducibility and consistency across experiments, thereby strengthening the validity of research findings.

For researchers and clinicians aiming to advance their understanding of PLD5’s biological functions and its implications in disease, PLD5 Gene Knockout Cell Lines represent a cutting-edge resource. Leveraging these models can accelerate discoveries that may lead to innovative therapeutic strategies.

Our company prides itself on its commitment to quality and innovation in providing advanced biological products. We utilize state-of-the-art technology and expertise to deliver exceptional tools that empower the scientific community in their quest for knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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