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PLAC8 Knockout Cell Lines

Gene: PLAC8

Official Full Name: placenta associated 8provided by HGNC

Gene Summary: Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Predicted to be located in azurophil granule lumen and extracellular region. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06656 PLAC8 Knockout cell line (HeLa) Human PLAC8 1:3~1:6 Negative Online Inquiry
KO06657 PLAC8 Knockout cell line (A549) Human PLAC8 1:3~1:4 Negative Online Inquiry

Background

PLAC8 Gene Knockout Cell Lines are specifically engineered cellular models that have had the PLAC8 gene inactivated. PLAC8, or Placenta-Associated 8, is implicated in various cellular processes, including cell proliferation, differentiation, and metabolism. The targeted knockout of this gene enables researchers to explore the functional role of PLAC8 in numerous biological contexts, providing insights into developmental biology, cancer research, and metabolic disorders.

These cell lines operate through a precise genome editing technique, often utilizing CRISPR-Cas9 technology, which induces a double-strand break at the PLAC8 locus, leading to insertions or deletions that result in gene disruption. By knocking out PLAC8, researchers can assess the resultant phenotypic changes and molecular pathways affected by its absence. This enables the elucidation of the gene's role in physiological and pathological conditions more accurately than with traditional approaches.

The scientific importance of PLAC8 Gene Knockout Cell Lines lies in their application across various research fields, including stem cell research, oncology, and metabolic disease modeling. Their use can significantly enhance our understanding of the intricacies of gene function and regulation in cellular mechanisms, which is critical for translational research.

What sets these knockout cell lines apart from alternatives is their validation through rigorous quality control, ensuring reproducibility and reliability in experimental results. Moreover, their customization for specific research needs allows for targeted studies that can significantly accelerate discoveries and therapeutic developments.

Researchers and clinicians targeting molecular pathways relevant to PLAC8 will find immense value in these knockout cell lines, enabling more insightful investigations into pathophysiology and potential treatments. Our company prides itself on its commitment to innovation and excellence in providing high-quality biological products, designed for optimal performance in both research and clinical applications. With PLAC8 Gene Knockout Cell Lines, we empower scientists to push the boundaries of their research and drive forward the discoveries that can change lives.

Please note that all services are for research use only. Not intended for any clinical use.

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