Gene: PLAA
Official Full Name: phospholipase A2 activating proteinprovided by HGNC
Gene Summary: Predicted to enable ubiquitin binding activity. Involved in cellular response to lipopolysaccharide; macroautophagy; and positive regulation of phospholipase A2 activity. Located in cytoplasm; extracellular exosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03704 | PLAA Knockout cell line (HeLa) | Human | PLAA | 1:3~1:6 | Negative | Online Inquiry |
KO03705 | PLAA Knockout cell line (HCT 116) | Human | PLAA | 1:2~1:4 | Negative | Online Inquiry |
KO03706 | PLAA Knockout cell line (HEK293) | Human | PLAA | 1:3~1:6 | Negative | Online Inquiry |
KO03707 | PLAA Knockout cell line (A549) | Human | PLAA | 1:3~1:4 | Negative | Online Inquiry |
PLAA Gene Knockout Cell Lines are genetically modified cell lines specifically designed to facilitate research into the functions and implications of the PLAA gene. By employing CRISPR-Cas9 technology, these cell lines have had the PLAA gene disrupted, enabling researchers to study the resultant phenotypic and molecular changes in a controlled environment. This knockout approach allows for a deep investigation into the gene’s role in cellular processes such as protein degradation, stress response, and signal transduction.
The primary mechanism by which PLAA knockout cell lines operate revolves around the absence of functional PLAA protein, leading to altered pathways that researchers can analyze to decode its biological significance. Understanding these functions is crucial, as PLAA has been linked to various pathologies, including neurodegenerative diseases and cancer progression. Hence, these cell lines hold tremendous potential for elucidating the underlying mechanisms of disease and discovering new therapeutic targets.
In both research and clinical settings, PLAA Gene Knockout Cell Lines provide invaluable insights into gene function and regulation. They serve as an excellent platform for drug screening, genetic studies, and validating new therapeutic strategies. The specific advantages of utilizing these cell lines include their reliable genetic alterations and reproducible results, contributing to stronger research outcomes compared to other models that may lack these attributes.
Researchers and clinicians will find considerable value in PLAA Gene Knockout Cell Lines due to their ability to streamline experiments and accelerate discoveries, thereby enhancing the overall efficiency of research projects. With an unwavering commitment to quality and user support, our company specializes in advanced cellular models and is poised to assist scientists in unlocking the complexities of gene functions through innovative solutions tailored to their research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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