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PITPNM2 Knockout Cell Lines

Gene: PITPNM2

Official Full Name: phosphatidylinositol transfer protein membrane associated 2provided by HGNC

Gene Summary: PITPNM2 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15109 PITPNM2 Knockout cell line (HeLa) Human PITPNM2 1:3~1:6 Negative Online Inquiry
KO15110 PITPNM2 Knockout cell line (HCT 116) Human PITPNM2 1:2~1:4 Negative Online Inquiry
KO15111 PITPNM2 Knockout cell line (HEK293) Human PITPNM2 1:3~1:6 Negative Online Inquiry
KO15112 PITPNM2 Knockout cell line (A549) Human PITPNM2 1:3~1:4 Negative Online Inquiry

Background

PITPNM2 Gene Knockout Cell Lines are genetically engineered models that have undergone targeted gene disruption to eliminate the expression of the phosphatidylinositol transfer protein, membrane-associated 2 (PITPNM2) gene. These cell lines provide a powerful tool for researchers investigating the functional roles of PITPNM2 in cellular processes such as membrane trafficking, signal transduction, and lipid metabolism. By creating a knockout of this gene, scientists can elucidate the specific pathways and mechanisms through which PITPNM2 operates, allowing for a deeper understanding of its contributions to cellular homeostasis.

The primary function of PITPNM2 involves the transfer of phosphatidylinositol and other lipids between cellular membranes, which is critical in processes like vesicle formation and cell signaling. The knockout of this gene provides a unique opportunity to explore its involvement in various physiological and pathological states, including cancer, neurodegenerative diseases, and metabolic disorders. In research and clinical settings, these cell lines can serve as vital models for drug testing, disease modeling, and the development of therapeutic strategies.

One of the key advantages of using PITPNM2 Gene Knockout Cell Lines is the specificity and accuracy of the gene-editing technology employed, which minimizes off-target effects that may confound experimental outcomes. Unlike other gene silencing methods such as RNA interference, knockout models provide a more definitive approach to studying the complete loss of gene function, thereby yielding clearer insights into the gene’s biological roles.

For researchers and clinicians, the value of these cell lines lies not just in their utility in basic research but also in their potential to contribute to the development of targeted therapies aimed at diseases associated with PITPNM2 dysregulation. By harnessing these genetically modified cell lines, users can conduct experiments with enhanced reproducibility and reliability, leading to innovative breakthroughs in understanding complex biological processes.

Our company brings years of expertise in developing high-quality genetic models, ensuring that our PITPNM2 Gene Knockout Cell Lines meet rigorous scientific standards while providing exceptional performance for diverse research applications.

Please note that all services are for research use only. Not intended for any clinical use.

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