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PITPNC1 Knockout Cell Lines

Gene: PITPNC1

Official Full Name: phosphatidylinositol transfer protein cytoplasmic 1provided by HGNC

Gene Summary: This gene encodes a member of the phosphatidylinositol transfer protein family. The encoded cytoplasmic protein plays a role in multiple processes including cell signaling and lipid metabolism by facilitating the transfer of phosphatidylinositol between membrane compartments. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 1. [provided by RefSeq, May 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28222 PITPNC1 Knockout cell line (HeLa) Human PITPNC1 1:3~1:6 Negative Online Inquiry
KO28223 PITPNC1 Knockout cell line (HCT 116) Human PITPNC1 1:2~1:4 Negative Online Inquiry
KO28224 PITPNC1 Knockout cell line (HEK293) Human PITPNC1 1:3~1:6 Negative Online Inquiry
KO28225 PITPNC1 Knockout cell line (A549) Human PITPNC1 1:3~1:4 Negative Online Inquiry

Background

PITPNC1 Gene Knockout Cell Lines are advanced cellular models designed to facilitate the study of cytosolic phosphoinositide transfer proteins and their role in various biological processes. These knockout cell lines are generated to exhibit a targeted disruption of the PITPNC1 gene, allowing researchers to investigate its functions and the downstream effects of its absence on cellular signaling pathways, migration, and proliferation.

These cell lines operate through the precise elimination of PITPNC1 expression, which is crucial for lipid signaling and membrane dynamics. By knocking out this gene, researchers can elucidate the significance of PITPNC1 in processes such as signal transduction, cellular metabolism, and immune response, making it a valuable tool for both basic and translational research.

The scientific importance of PITPNC1 knockout cell lines extends to various fields, including oncology, neurobiology, and immunology. Understanding the role of PITPNC1 in these contexts can lead to insights into disease mechanisms and potential therapeutic targets. For instance, aberrations in lipid signaling are commonly associated with cancer development and progression, thus these cell lines serve as essential models for drug discovery and testing.

In comparison to other existing cell lines, the PITPNC1 knockout models provide a highly specific approach to dissecting gene function without the confounding effects often observed in partial knockdowns or overexpression systems. This specificity allows for more accurate predictions of biological outcomes, enhancing the reproducibility and reliability of experimental results.

The value of PITPNC1 Gene Knockout Cell Lines to researchers, clinicians, and pharmaceutical developers lies in their ability to reveal previously obscured pathways and mechanisms essential in health and disease. The application of these models can significantly expedite research findings, from fundamental discoveries to potential clinical applications.

Our company brings unparalleled expertise in the design and production of genetically modified cell lines, ensuring a product offering that meets the highest standards of quality and reliability for the scientific community. With a commitment to advancing research, we provide tools that empower breakthroughs in understanding complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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