Gene: PIK3AP1
Official Full Name: phosphoinositide-3-kinase adaptor protein 1provided by HGNC
Gene Summary: Predicted to enable phosphatidylinositol 3-kinase regulatory subunit binding activity and signaling receptor binding activity. Predicted to be involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; regulation of inflammatory response; and regulation of innate immune response. Predicted to be located in membrane. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10206 | PIK3AP1 Knockout cell line (HCT 116) | Human | PIK3AP1 | 1:2~1:4 | Negative | Online Inquiry |
KO10207 | PIK3AP1 Knockout cell line (HEK293) | Human | PIK3AP1 | 1:3~1:6 | Negative | Online Inquiry |
KO10208 | PIK3AP1 Knockout cell line (A549) | Human | PIK3AP1 | 1:3~1:4 | Negative | Online Inquiry |
PIK3AP1 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to study the functional implications of the PIK3AP1 gene, which plays a crucial role in immune signaling pathways. By deleting this gene, researchers can investigate its effects on cellular processes such as proliferation, differentiation, and apoptosis, particularly in the context of hematopoietic cell function and immune response regulation.
The key mechanism of PIK3AP1 involves its interaction with several signaling pathways, notably the phosphoinositide 3-kinase (PI3K) pathway, which is vital for cell growth and survival. By utilizing these knockout cell lines, scientists can elucidate the downstream effects of PIK3AP1 loss, providing insights into immune dysregulation associated with various diseases, including autoimmune disorders and certain cancers.
The scientific importance of PIK3AP1 Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, these cell lines act as vital tools for elucidating the molecular mechanisms of diseases linked to dysregulated immune responses. Clinically, insights gleaned from these studies can pave the way for the development of novel therapeutic strategies that target immune modulation, thereby enhancing treatment regimens in patients with immune-related conditions.
Compared to alternative models, our PIK3AP1 knockout cell lines deliver highly specific and reproducible results, backed by precise genetic modification techniques such as CRISPR/Cas9. This specificity reduces background noise commonly encountered in broader models, enabling a clearer understanding of gene function and its implications in complex biological systems.
For researchers and clinicians alike, the value of PIK3AP1 Gene Knockout Cell Lines lies in their capacity to accelerate discovery and innovation. These cell lines empower scientists to explore intricate cellular pathways and contribute meaningfully to advancing medical research.
As a leader in the field of biological products, our company is committed to providing researchers with high-quality, expertly validated genetic models that support groundbreaking discoveries. With our extensive experience and focus on innovation, we offer a distinctly reliable resource for boosting scientific understanding and therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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