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PID1 Knockout Cell Lines

Gene: PID1

Official Full Name: phosphotyrosine interaction domain containing 1provided by HGNC

Gene Summary: Involved in several processes, including negative regulation of D-glucose import; negative regulation of phosphate metabolic process; and positive regulation of metabolic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15155 PID1 Knockout cell line (HeLa) Human PID1 1:3~1:6 Negative Online Inquiry
KO15156 PID1 Knockout cell line (A549) Human PID1 1:3~1:4 Negative Online Inquiry

Background

PID1 Gene Knockout Cell Lines are innovative cellular models specifically engineered to lack the expression of the protein encoded by the PID1 gene (Phosphotyrosine Interaction Domain Containing 1). These knockout cell lines serve as an essential tool for researchers to dissect the biological roles of PID1, which is implicated in various metabolic pathways, insulin signaling, and potentially cancer progression. By studying these cells, scientists can gain insights into the mechanistic pathways influenced by PID1 and elucidate the gene's functions in cellular homeostasis.

The primary mechanism of action lies in the absence of PID1-related signaling, which enables researchers to observe phenotypic and functional alterations in the cellular milieu. This can include changes in glucose metabolism, cellular proliferation, and response to growth factors. These insights are critical as they expand our understanding of PID1's contributions to diseases characterized by metabolic dysregulation, such as type 2 diabetes and cancer.

The scientific importance of PID1 Gene Knockout Cell Lines cannot be overstated. In research settings, they provide a robust platform for functional assays, drug testing, and exploration of therapeutic targets, offering a means to validate hypotheses surrounding PID1’s role. Clinicians can leverage these findings to identify potential therapeutic strategies aimed at mitigating diseases linked with PID1 dysregulation.

Compared to conventional cell lines, these knockout models offer unique advantages, including a targeted deletion that eliminates confounding variables and a consistent genetic background, enhancing reproducibility and reliability in experimental outcomes. Unlike standard gene expression manipulation techniques, PID1 Gene Knockout Cell Lines provide a stable and permanent deletion, facilitating long-term studies.

For researchers, clinicians, and pharmaceutical developers focused on metabolic disorders, these knockout cell lines represent a significant value—empowering them to unlock new potential for therapeutic interventions and advance our understanding of PID1-related biology. At [Your Company Name], we pride ourselves on our expertise in producing high-quality biological products and are committed to supporting the scientific community with tools that drive innovation and discovery in health and disease research.

Please note that all services are for research use only. Not intended for any clinical use.

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