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PIBF1 Knockout Cell Lines

Gene: PIBF1

Official Full Name: progesterone immunomodulatory binding factor 1provided by HGNC

Gene Summary: This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31847 PIBF1 Knockout cell line (HeLa) Human PIBF1 1:3~1:6 Negative Online Inquiry
KO31848 PIBF1 Knockout cell line (HCT 116) Human PIBF1 1:2~1:4 Negative Online Inquiry
KO31849 PIBF1 Knockout cell line (HEK293) Human PIBF1 1:3~1:6 Negative Online Inquiry
KO31850 PIBF1 Knockout cell line (A549) Human PIBF1 1:3~1:4 Negative Online Inquiry

Background

PIBF1 Gene Knockout Cell Lines represent a powerful experimental tool designed for probing the functional roles of the PIBF1 gene, which is implicated in numerous biological processes, including cell signaling, immune responses, and cancer progression. By utilizing CRISPR/Cas9 technology, these knockout cell lines provide a precise and efficient means to investigate the cellular mechanisms that are influenced by PIBF1 and its associated pathways.

The primary function of the PIBF1 knockout cell lines is to enable researchers to assess the impact of PIBF1 gene disruption on cellular behavior. When the PIBF1 gene is knocked out, cellular responses such as proliferation, migration, and apoptosis can be meticulously analyzed to unveil the gene's contribution to various physiological and pathological processes. This methodology allows for the exploration of compensatory mechanisms that may arise in the absence of PIBF1, enhancing our understanding of gene interactions and regulatory networks.

From a scientific perspective, PIBF1 knockout cell lines provide significant applications in both research and clinical settings. Researchers can leverage these models to investigate the underlying mechanisms of diseases, potentially leading to novel therapeutic targets, particularly in oncology and immunology. The insights gained from these studies can facilitate the development of innovative strategies for disease management, including targeted therapies that focus on reparative and modulatory pathways driven by PIBF1.

A unique advantage of PIBF1 knockout cell lines lies in their high specificity and reproducibility, which offer a more reliable alternative to traditional gene silencing methods, such as RNA interference. With full gene knockout, researchers can ascertain definitive outcomes without the ambiguities associated with partial gene silencing. This specificity ensures that the resulting data is robust and relevant, thereby strengthening scientific conclusions.

Ultimately, PIBF1 Gene Knockout Cell Lines stand as a valuable asset for researchers, clinicians, and biotechnology companies aiming to unveil the complex interactions dictated by the PIBF1 gene. By integrating these advanced models into research agendas, users can enhance the efficacy of their studies, contributing to the broader understanding of gene function in health and disease. Backed by our company's commitment to providing cutting-edge tools and extensive expertise in genetic engineering, we are poised to support your research initiatives with high-quality, reliable biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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