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PHACTR2 Knockout Cell Lines

Gene: PHACTR2

Official Full Name: phosphatase and actin regulator 2provided by HGNC

Gene Summary: Predicted to enable actin binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to be located in plasma membrane and platelet alpha granule membrane. Implicated in Parkinson's disease and multiple sclerosis. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32820 PHACTR2 Knockout cell line (HeLa) Human PHACTR2 1:3~1:6 Negative Online Inquiry
KO32821 PHACTR2 Knockout cell line (HCT 116) Human PHACTR2 1:2~1:4 Negative Online Inquiry
KO32822 PHACTR2 Knockout cell line (HEK293) Human PHACTR2 1:3~1:6 Negative Online Inquiry
KO32823 PHACTR2 Knockout cell line (A549) Human PHACTR2 1:3~1:4 Negative Online Inquiry

Background

PHACTR2 Gene Knockout Cell Lines are genetically modified cell lines in which the PHACTR2 gene has been selectively disrupted. This innovative biological tool allows researchers to investigate the role of the PHACTR2 gene in various physiological and pathological processes. The knockout of the PHACTR2 gene can significantly affect cellular functions, including cytoskeletal organization, cell signaling pathways, and cellular response to stress, thereby providing a unique window into the gene's contributions to diseases such as cancer and neurodegenerative disorders.

The key mechanism of action involves the use of CRISPR-Cas9 technology, which enables precise editing of the genome. By targeting specific sequences within the PHACTR2 gene, researchers can create a loss-of-function model that facilitates the examination of gene function through various phenotypic changes in the cell lines. This targeted approach provides definitive insights into gene interactions and pathways, thereby advancing the understanding of disease mechanisms.

The scientific importance of PHACTR2 Gene Knockout Cell Lines extends beyond fundamental research; they offer significant applications in drug discovery and therapeutic development. By elucidating the role of PHACTR2 in specific cellular contexts, these cell lines can help identify potential drug targets and contribute to the development of more effective treatments.

Compared to alternative knockout models, this product stands out due to its high specificity and efficiency in gene disruption, coupled with robust validation through multiple assays. The availability of well-characterized cell lines ensures reproducibility and reliability of experimental outcomes, providing researchers and clinicians with a trusted platform for their studies.

For researchers and clinicians dedicated to exploring the complexities of gene functions in health and disease, the PHACTR2 Gene Knockout Cell Lines represent an indispensable resource. They empower users by offering high-quality models that streamline research processes and support innovative discoveries.

Our company specializes in the development of advanced genetic tools, ensuring that each product, including the PHACTR2 Gene Knockout Cell Lines, is backed by rigorous scientific expertise and a commitment to enhancing biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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