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PGAP4 Knockout Cell Lines

Gene: PGAP4

Official Full Name: post-GPI attachment to proteins GalNAc transferase 4provided by HGNC

Gene Summary: Enables glycosyltransferase activity. Involved in GPI anchor biosynthetic process. Located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04984 PGAP4 Knockout cell line (HeLa) Human PGAP4 1:3~1:6 Negative Online Inquiry
KO04985 PGAP4 Knockout cell line (HCT 116) Human PGAP4 1:2~1:4 Negative Online Inquiry
KO04986 PGAP4 Knockout cell line (HEK293) Human PGAP4 1:3~1:6 Negative Online Inquiry
KO04987 PGAP4 Knockout cell line (A549) Human PGAP4 1:3~1:4 Negative Online Inquiry

Background

PGAP4 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed to support research in gene function, signaling pathways, and disease mechanisms. These cell lines are created by targeting the PGAP4 gene, which encodes a glycosylphosphatidylinositol (GPI)-anchored protein involved in cellular processes such as signal transduction and cellular adhesion.

The key function of PGAP4 Gene Knockout Cell Lines lies in their ability to elucidate the role of PGAP4 in various physiological and pathological processes, including immune responses and cancer progression. By removing the PGAP4 gene, researchers can examine the resultant phenotypic and molecular changes, gaining insights into the gene’s contributions to cellular behavior and disease states. This knockout model is particularly valuable in studies exploring GPI-anchor related cellular interactions, offering a robust platform for functional genomics.

The scientific importance of PGAP4 Gene Knockout Cell Lines extends into both basic and applied research, including drug discovery and development. Their availability allows for high-throughput screening of pharmaceutical compounds that target pathways associated with PGAP4 dysregulation. Furthermore, these cell lines are essential for understanding genetic diseases linked to GPI anchoring, thus bridging the gap between basic research and clinical applications.

Distinct advantages of PGAP4 Gene Knockout Cell Lines include their specificity and reliability compared to alternative models, such as siRNA-mediated knockdown, which may result in incomplete gene silencing. Additionally, these knockout lines are routinely validated, ensuring consistency in experimental results, which is crucial for reproducibility in scientific research.

For researchers and clinicians focused on unraveling complex biological systems or developing therapeutic interventions, PGAP4 Gene Knockout Cell Lines provide an invaluable resource, facilitating innovative discoveries and advancing scientific knowledge. By choosing our product, you benefit not only from high-quality cell lines but also from our company’s extensive expertise in cell line development, genetic engineering, and dedication to supporting the scientific community with superior biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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