Gene: PEX11G
Official Full Name: peroxisomal biogenesis factor 11 gammaprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the PEX11 family. This family is reported to regulate the number and size of peroxisomes in evolutionarily distant organisms. The protein encoded by this gene may induce clustering of peroxisomes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22457 | PEX11G Knockout cell line (HCT 116) | Human | PEX11G | 1:2~1:4 | Negative | Online Inquiry |
KO22458 | PEX11G Knockout cell line (HEK293) | Human | PEX11G | 1:3~1:6 | Negative | Online Inquiry |
KO22459 | PEX11G Knockout cell line (A549) | Human | PEX11G | 1:3~1:4 | Negative | Online Inquiry |
PEX11G gene knockout cell lines are engineered cell lines designed to specifically lack the expression of the PEX11G gene, which plays a crucial role in peroxisome biogenesis and proliferation. By employing CRISPR-Cas9 technology, these knockout cell lines provide a powerful tool for studying the functional implications of PEX11G, including its involvement in lipid metabolism and cellular signaling pathways.
The primary function of PEX11G is to regulate peroxisome homeostasis, a vital process that impacts various metabolic pathways. In essence, the PEX11G gene acts as a promoter of peroxisome division, influencing the number and function of these organelles in eukaryotic cells. The knockout of PEX11G allows researchers to elucidate the gene's specific contributions to peroxisome-related metabolic disorders and provides a platform for testing hypotheses regarding the interplay between peroxisomes and cellular health.
Scientifically, these knockout cell lines are invaluable for research in fields ranging from molecular biology to clinical applications. They enable the exploration of the consequences of peroxisomal dysfunction, which is associated with several genetic disorders, including Zellweger spectrum disorders and X-linked adrenoleukodystrophy. Furthermore, the insights garnered from studying these cell lines can lead to novel therapeutic interventions and enhance the understanding of metabolic regulation in health and disease.
What sets our PEX11G gene knockout cell lines apart from alternatives is their high level of specificity and efficiency achieved through advanced gene-editing techniques. Unlike traditional methods that may inadvertently affect other genes, our product ensures precise deletion of the PEX11G gene, minimizing off-target effects. This specificity allows for more reliable data and reproducibility in experimental designs.
For researchers and clinicians, these knockout cell lines represent a significant advancement in the ability to study peroxisome dynamics and associated metabolic disorders. Their availability facilitates groundbreaking research and aids in devising innovative strategies for therapeutic targeting.
Our company is dedicated to providing cutting-edge biological products backed by rigorous scientific research and development. With years of expertise in gene editing technology and a commitment to empowering scientific discovery, we stand at the forefront of delivering high-quality solutions to enhance research efficacy and accelerate clinical insights.
Please note that all services are for research use only. Not intended for any clinical use.
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