Gene: PERM1
Official Full Name: PPARGC1 and ESRR induced regulator, muscle 1provided by HGNC
Gene Summary: Involved in response to muscle activity. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24621 | PERM1 Knockout cell line (HCT 116) | Human | PERM1 | 1:2~1:4 | Negative | Online Inquiry |
PERM1 Gene Knockout Cell Lines are genetically modified cellular models designed to study the specific role of the PERM1 gene in various biological processes. These cell lines have undergone CRISPR-Cas9 gene editing techniques to disrupt the expression of the PERM1 gene, facilitating precise investigations into the gene's functions, interactions, and implications in cellular mechanisms.
The primary function of PERM1 Gene Knockout Cell Lines is to provide researchers a controlled system to evaluate the consequences of PERM1 deficiency. The deliberate knockout of this gene allows for the understanding of its role in cellular pathways, differentiation, apoptosis, and disease mechanisms. By observing phenotypic changes and gene expression variations when PERM1 is absent, researchers can elucidate the biological significance of this gene in both normal physiology and pathophysiology.
These cell lines hold significant scientific importance as they serve as powerful tools in both fundamental research and therapeutic contexts. Investigators can apply them in studies related to cancer biology, neurodegenerative diseases, and developmental biology, aiding in the identification of potential therapeutic targets or biomarkers. The insights gained from experiments using these cell lines could directly contribute to the advancement of genetic therapies and innovative treatment approaches.
One of the key advantages of PERM1 Gene Knockout Cell Lines is their reliability and reproducibility. Compared to transient knockdown methods that may yield inconsistent results, permanent knockouts generate stable models that faithfully mimic loss-of-function conditions. Additionally, these cell lines are readily adaptable for high-throughput screening, allowing for the efficient evaluation of compounds that could modulate PERM1-related pathways.
For researchers and clinicians focused on gene function and therapeutic development, the value of utilizing PERM1 Gene Knockout Cell Lines cannot be overstated. They not only streamline experimental workflows but also enhance the validity of findings, ultimately leading to a more profound understanding of the underlying biology.
Our company specializes in providing advanced biological tools and resources. With expertise in genetic engineering and cell line development, we are committed to supporting the scientific community with high-quality products that foster innovative research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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