Gene: PELO
Official Full Name: pelota mRNA surveillance and ribosome rescue factorprovided by HGNC
Gene Summary: This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21881 | PELO Knockout cell line (HeLa) | Human | PELO | 1:3~1:6 | Negative | Online Inquiry |
KO21882 | PELO Knockout cell line (HCT 116) | Human | PELO | 1:2~1:4 | Negative | Online Inquiry |
KO21883 | PELO Knockout cell line (HEK293) | Human | PELO | 1:3~1:6 | Negative | Online Inquiry |
PELO Gene Knockout Cell Lines are genetically modified cell lines designed to specifically knock out the PELO gene, crucial in cellular processes such as translation regulation and cellular stress response. By using advanced CRISPR-Cas9 gene-editing technology, these cell lines enable researchers to explore the functional role of PELO in various biological contexts. The knockout mechanism selectively disables the gene’s expression, leading to focused studies on its contributions to cell growth, differentiation, and apoptosis.
Functionally, the PELO Gene Knockout Cell Lines provide a valuable model for dissecting the pathways involving translational repression and stress granule formation. Researchers can investigate how the absence of the PELO protein affects not only cellular homeostasis but also the overall stress response, paving the way for enhanced understanding of conditions such as cancer and neurodegenerative diseases. In clinical research, these knockout lines serve as excellent models for drug discovery and testing, allowing scientists to identify potential therapeutic targets and evaluate drug efficacy in a controlled environment.
When compared to conventional gene knockdown methods like siRNA or shRNA, the PELO Gene Knockout Cell Lines offer several advantages. They provide robust and permanent alterations to the genome, leading to consistent and reproducible research outcomes. This is complemented by the ease of use and adaptability for high-throughput screening applications, making them an essential tool for modern molecular biology.
The value of PELO Gene Knockout Cell Lines extends to multidisciplinary research environments, providing critical insights for biologists, pharmacologists, and geneticists. By utilizing these advanced cell lines, researchers can advance their understanding of the PELO gene's roles in cellular function and its implications in health and disease.
At our company, we specialize in the production of high-quality, custom-engineered biological products like the PELO Gene Knockout Cell Lines, backed by a team of experts committed to supporting your research endeavors with precision, reliability, and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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