Gene: PEF1
Official Full Name: penta-EF-hand domain containing 1provided by HGNC
Gene Summary: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20379 | PEF1 Knockout cell line (HeLa) | Human | PEF1 | 1:3~1:6 | Negative | Online Inquiry |
KO20380 | PEF1 Knockout cell line (HCT 116) | Human | PEF1 | 1:2~1:4 | Negative | Online Inquiry |
KO20381 | PEF1 Knockout cell line (HEK293) | Human | PEF1 | 1:3~1:6 | Negative | Online Inquiry |
KO20382 | PEF1 Knockout cell line (A549) | Human | PEF1 | 1:3~1:4 | Negative | Online Inquiry |
PEF1 Gene Knockout Cell Lines are specially engineered cellular models created to eliminate the expression of the PEF1 gene, a crucial factor involved in various cellular processes, including proliferation, differentiation, and response to environmental stimuli. Utilizing advanced CRISPR-Cas9 gene-editing technologies, these cell lines provide a versatile platform for researchers to study the functional role of the PEF1 gene and its implications in cell biology, disease modeling, and therapeutic development.
The primary function of PEF1 Gene Knockout Cell Lines is to enable researchers to investigate the cellular pathways impacted by the absence of PEF1 expression. By elucidating the downstream effects and compensatory mechanisms, scientists can gain insights into the gene's role in various physiological contexts, including metabolic regulation and cancer biology. This understanding paves the way for potential translational applications in drug discovery and personalized medicine.
The scientific importance of these cell lines extends into both basic research and clinical settings, serving as a model for studying diseases associated with PEF1 dysregulation. By facilitating high-throughput screening, these cell lines can significantly expedite the identification of novel therapeutic candidates and molecular targets.
One of the distinctive advantages of PEF1 Gene Knockout Cell Lines is their precise genetic modification, which minimizes off-target effects commonly associated with alternative gene-editing methods. This specificity not only enhances the reliability of experimental outcomes but also instills confidence in the reproducibility of results, crucial for regulatory compliance in clinical research.
For researchers and clinicians focused on gene function analysis and disease mechanism exploration, PEF1 Gene Knockout Cell Lines represent a powerful tool that can enrich their investigations and lead to impactful discoveries. The combination of our rigorous validation processes and in-depth expertise in cell line development ensures that you receive a high-quality product tailored to your research needs.
Our company is committed to advancing scientific research and innovation by providing precisely engineered biological products designed to facilitate groundbreaking discoveries in genetics and disease biology.
Please note that all services are for research use only. Not intended for any clinical use.
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