Gene: PDZD7
Official Full Name: PDZ domain containing 7provided by HGNC
Gene Summary: This gene encodes a ciliary protein homologous to proteins which are mutated in Usher syndrome patients, and mutations and translocations involving this gene have been associated with two types of Usher syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15248 | PDZD7 Knockout cell line (HeLa) | Human | PDZD7 | 1:3~1:6 | Negative | Online Inquiry |
KO15249 | PDZD7 Knockout cell line (HCT 116) | Human | PDZD7 | 1:2~1:4 | Negative | Online Inquiry |
KO15250 | PDZD7 Knockout cell line (HEK293) | Human | PDZD7 | 1:3~1:6 | Negative | Online Inquiry |
KO15251 | PDZD7 Knockout cell line (A549) | Human | PDZD7 | 1:3~1:4 | Negative | Online Inquiry |
PDZD7 Gene Knockout Cell Lines are advanced biological tools designed for in-depth research into cellular mechanisms and gene function. These cell lines are created by specifically targeting and knocking out the PDZD7 gene, which encodes a protein involved in critical cellular processes, including signaling pathways related to synaptic function and cellular adhesion. By employing CRISPR-Cas9 technology or homologous recombination methods, these knockout cell lines enable researchers to elucidate the role of PDZD7 in physiological and pathological contexts.
The primary function of PDZD7 Gene Knockout Cell Lines lies in their ability to allow researchers to investigate the consequences of PDZD7 loss-of-function in vitro. This enables studies focused on various diseases, particularly in areas like neurobiology, where PDZD7 has been implicated in synaptic plasticity and neurodegenerative processes. The mechanisms by which these cell lines operate provide insights into gene-gene and gene-environment interactions, essential for understanding cellular dynamics.
In addition to enhancing basic research outcomes, these knockout cell lines have significant applications in drug discovery and development, particularly when screening for therapeutic compounds that impact synaptic functions or related pathways. The PDZD7 knockout model serves as a vital platform for validation of therapeutic targets in neurobiology and may offer insights into novel therapeutic strategies.
When compared to traditional approaches, such as siRNA-mediated knockdown, PDZD7 Gene Knockout Cell Lines possess distinct advantages. They create stable genetic modifications that provide a more reliable and reproducible cellular environment over time, critical for long-term experiments and therapeutic evaluations.
The value of these cell lines to researchers and clinicians is multifaceted; they streamline studies that aim to unravel the complexities of genetic regulation in disease pathways, facilitating discoveries that can lead to innovative treatment plans. Moreover, scientists can explore new avenues of research with confidence, knowing they are working with advanced models that accurately mimic the absence of PDZD7.
At our company, we pride ourselves on our extensive expertise in cell line development and genetic engineering. Our commitment to high-quality biological products ensures that our customers receive reliable models tailored for groundbreaking research applications.
Please note that all services are for research use only. Not intended for any clinical use.
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