Gene: PDGFC
Official Full Name: platelet derived growth factor Cprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09065 | PDGFC Knockout cell line (HeLa) | Human | PDGFC | 1:3~1:6 | Negative | Online Inquiry |
KO09066 | PDGFC Knockout cell line (HCT 116) | Human | PDGFC | 1:2~1:4 | Negative | Online Inquiry |
KO09067 | PDGFC Knockout cell line (HEK293) | Human | PDGFC | 1:3~1:6 | Negative | Online Inquiry |
KO09068 | PDGFC Knockout cell line (A549) | Human | PDGFC | 1:3~1:4 | Negative | Online Inquiry |
PDGFC Gene Knockout Cell Lines are engineered cellular models that provide a crucial tool for studying the biological role of the Platelet-Derived Growth Factor C (PDGFC) gene. By employing CRISPR-Cas9 technology, these cell lines have been meticulously crafted to disregard the PDGFC gene's expression, allowing researchers to investigate the downstream effects and pathways influenced by this growth factor. PDGFC plays a significant role in various physiological and pathological processes, including cell proliferation, survival, and differentiation. By utilizing these knockout lines, researchers can elucidate the gene's involvement in diseases such as cancer, fibrotic disorders, and cardiovascular conditions.
The primary function of the PDGFC knockout cell lines lies in their ability to serve as a controlled environment for experimentation. By observing the cellular responses in the absence of PDGFC, researchers can generate insights into its signaling mechanisms and associated cellular behaviors. Such studies are essential in advancing our understanding of how PDGFC contributes to tumor microenvironments and tissue remodeling, thereby accelerating the discovery of novel therapeutic strategies.
The significance of PDGFC Gene Knockout Cell Lines extends to both basic research and clinical applications. They are invaluable for drug screening, biomarker identification, and the development of targeted therapies. In settings where alternative models may not accurately replicate human disease pathways, these knockout lines provide reproducible, human-relevant data critical for translational research.
A standout advantage of our PDGFC Gene Knockout Cell Lines resides in their robust performance, reliable genetic eliminates, and consistency across experiments, compared to conventional models which may present variability in gene expression. This reliability facilitates reproducibility and enhances the credibility of research outcomes, offering researchers a dependable platform for their studies.
For researchers and clinicians focused on understanding the complexities of PDGFC and its clinical implications, our engineering expertise ensures that these cell lines can integrate seamlessly into diverse experimental protocols. By choosing our PDGFC Gene Knockout Cell Lines, users gain access to high-quality, meticulously validated tools that can provide critical insights and propel scientific discovery in fields ranging from oncology to regenerative medicine. Our commitment to delivering exceptional scientific products stems from our state-of-the-art facilities and a dedicated team of experts in genetic engineering, ensuring that every product meets the highest standards of quality and reliability.
Please note that all services are for research use only. Not intended for any clinical use.
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