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PDCD5 Knockout Cell Lines

Gene: PDCD5

Official Full Name: programmed cell death 5provided by HGNC

Gene Summary: This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33518 PDCD5 Knockout cell line (HeLa) Human PDCD5 1:3~1:6 Negative Online Inquiry
KO33519 PDCD5 Knockout cell line (HCT 116) Human PDCD5 1:2~1:4 Negative Online Inquiry
KO33520 PDCD5 Knockout cell line (HEK293) Human PDCD5 1:3~1:6 Negative Online Inquiry
KO33521 PDCD5 Knockout cell line (A549) Human PDCD5 1:3~1:4 Negative Online Inquiry

Background

PDCD5 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the programmed cell death 5 (PDCD5) gene, which plays a crucial role in regulating apoptosis and cellular stress responses. By disrupting the PDCD5 gene, these cell lines provide valuable insights into the mechanisms of cell survival and death, making them essential tools for researchers investigating cancer biology, neurodegenerative diseases, and developmental processes.

The primary function of PDCD5 is to act as a pro-apoptotic factor, promoting cell death in response to various stressors. Knockout of this gene leads to enhanced cell survival, allowing researchers to study the implications of apoptosis dysregulation. The PDCD5 knockout cell lines serve as a platform for dissecting cell signaling pathways related to survival and apoptosis, thereby offering a deeper understanding of tumorigenesis and pathophysiology associated with numerous diseases.

The scientific significance of PDCD5 Gene Knockout Cell Lines is evident in their utility across various applications, from fundamental biological research to preclinical studies. They provide a robust model for testing therapeutic compounds and examining the potential for drug resistance in cancer therapies, facilitating the identification of novel targets for intervention. Additionally, these cell lines have the potential to accelerate the study of PDCD5's role in immune response and inflammation, highlighting their relevance in clinical settings.

Unlike traditional cell lines, which may still express varying levels of PDCD5, our knockout cell lines guarantee complete gene disruption, thereby providing a more consistent and reliable experimental environment. This specificity reduces variability in experimental results and enhances reproducibility, ultimately leading to more robust data interpretation.

Investing in PDCD5 Gene Knockout Cell Lines empowers researchers and clinicians to uncover the complexities of apoptosis and cellular response mechanisms. As they navigate the landscape of modern biology, access to these advanced cell models will significantly augment their research capabilities.

Our company specializes in providing high-quality biological products and tools that facilitate cutting-edge research. With expertise in gene editing technologies and a commitment to quality, we ensure that our PDCD5 Gene Knockout Cell Lines meet the rigorous standards expected by today’s scientists and researchers.

Please note that all services are for research use only. Not intended for any clinical use.

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