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PCYOX1 Knockout Cell Lines

Gene: PCYOX1

Official Full Name: prenylcysteine oxidase 1provided by HGNC

Gene Summary: Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product (Tschantz et al., 1999 [PubMed 10585463]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22528 PCYOX1 Knockout cell line (HeLa) Human PCYOX1 1:3~1:6 Negative Online Inquiry
KO22529 PCYOX1 Knockout cell line (HCT 116) Human PCYOX1 1:2~1:4 Negative Online Inquiry
KO22530 PCYOX1 Knockout cell line (HEK293) Human PCYOX1 1:3~1:6 Negative Online Inquiry
KO22531 PCYOX1 Knockout cell line (A549) Human PCYOX1 1:3~1:4 Negative Online Inquiry

Background

PCYOX1 Gene Knockout Cell Lines are a highly specialized tool designed for researchers investigating the physiological roles of the PCYOX1 gene, which encodes a critical enzyme involved in cellular lipid metabolism and energy homeostasis. These cell lines are engineered using advanced CRISPR-Cas9 gene editing technology to create specific knockouts of the PCYOX1 gene, thus allowing for the in-depth study of its functional impacts on cellular processes.

The primary mechanism of these knockout cell lines involves the absence of the PCYOX1 protein, which has been implicated in various metabolic pathways. Researchers can observe the resultant phenotypic changes, alterations in lipid profiles, and shifts in cellular signaling cascades to elucidate the role of PCYOX1 in disease models such as obesity, diabetes, and metabolic syndrome. This provides a versatile platform for both basic research and translational applications in understanding metabolic disorders.

The scientific significance of PCYOX1 Gene Knockout Cell Lines is underscored by their utility in drug discovery and development, where understanding the basic mechanisms of lipid metabolism can lead to new therapeutic targets. Furthermore, these cell lines facilitate high-throughput screening of compounds that may selectively modulate PCYOX1 activity, enhancing the drug development pipeline.

Unique advantages of our PCYOX1 Gene Knockout Cell Lines over conventional alternatives include their precise genetic modification, leading to more reproducible and reliable experimental outcomes. The comprehensive genomic validation accompanying these cell lines ensures high confidence in their utility for both in vitro and potential in vivo studies.

For researchers and clinicians, the value of these knockout cell lines lies in their potential to accelerate discoveries in metabolic research, identify novel biomarkers, and ultimately develop innovative therapeutic strategies. Our company prides itself on its cutting-edge biotechnology solutions, backed by a team of experts committed to supporting the scientific community with high-quality and reliable tools for advancing biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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