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PCTP Knockout Cell Lines

Gene: PCTP

Official Full Name: phosphatidylcholine transfer proteinprovided by HGNC

Gene Summary: Enables phosphatidylcholine binding activity and phosphatidylcholine transporter activity. Involved in phospholipid transport. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15280 PCTP Knockout cell line (HeLa) Human PCTP 1:3~1:6 Negative Online Inquiry
KO15281 PCTP Knockout cell line (HCT 116) Human PCTP 1:2~1:4 Negative Online Inquiry
KO15282 PCTP Knockout cell line (HEK293) Human PCTP 1:3~1:6 Negative Online Inquiry
KO15283 PCTP Knockout cell line (A549) Human PCTP 1:3~1:4 Negative Online Inquiry

Background

PCTP Gene Knockout Cell Lines are genetically modified cell lines designed to eliminate the expression of the Phosphatidylcholine Transfer Protein (PCTP) gene, providing researchers with invaluable tools for studying the functional role of PCTP in cellular processes. Achieved through precise CRISPR/Cas9 technology, these knockout cell lines create a model that allows for the analysis of PCTP's involvement in lipid metabolism, cell signaling, and disease pathology. By disrupting the nucleotide sequence of the PCTP gene, these cell lines enable scientists to observe phenotypic changes that elucidate the protein's biological significance.

The key mechanism behind these cell lines involves targeted genome editing, which facilitates the creation of knockout models that can be utilized in various assays. This allows for straightforward investigation into the effects of PCTP deficiency on cellular physiology, including alterations in membrane composition, cholesterol homeostasis, and interactions with other signaling molecules. Such insights are critical in understanding the underlying mechanisms of metabolic diseases, neurodegenerative disorders, and cancer.

From a scientific perspective, PCTP Gene Knockout Cell Lines offer a range of applications, including drug discovery, functional genomics, and the elucidation of disease mechanisms. Their availability empowers researchers in both academic and clinical settings to conduct experiments that could lead to novel therapeutic interventions targeting lipid transport and metabolism.

Compared to alternative methods such as transient knockdowns or pharmacological inhibitors, our PCTP knockout lines provide a stable and reproducible system for long-term studies, minimizing variability and enhancing experimental rigor. Researchers can expect high-quality results that reflect PCTP’s role in a consistent and controlled environment, ultimately advancing their understanding of cellular dynamics.

By choosing PCTP Gene Knockout Cell Lines, researchers not only gain access to cutting-edge genetic tools but also benefit from our company’s extensive expertise in developing innovative biological products. Our commitment to quality and scientific excellence ensures that users receive reliable resources that can significantly contribute to their research objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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