Gene: PCNX1
Official Full Name: pecanex 1provided by HGNC
Gene Summary: This gene encodes an evolutionarily conserved transmembrane protein similar to the pecanex protein in Drosophila. The fly protein is a component of the Notch signaling pathway, which functions in several developmental processes. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30054 | PCNX1 Knockout cell line (HeLa) | Human | PCNX1 | 1:3~1:6 | Negative | Online Inquiry |
KO30055 | PCNX1 Knockout cell line (HCT 116) | Human | PCNX1 | 1:2~1:4 | Negative | Online Inquiry |
KO30056 | PCNX1 Knockout cell line (HEK293) | Human | PCNX1 | 1:3~1:6 | Negative | Online Inquiry |
KO30057 | PCNX1 Knockout cell line (A549) | Human | PCNX1 | 1:3~1:4 | Negative | Online Inquiry |
PCNX1 Gene Knockout Cell Lines are a highly specialized tool developed for the exploration of the functional role of the PCNX1 gene within various biological contexts. These cell lines are engineered through advanced CRISPR-Cas9 gene editing technology, resulting in specific deletions that lead to a total loss of PCNX1 expression. This precise modification enables researchers to investigate the gene's contributions to cellular processes such as proliferation, differentiation, and response to stressors.
The key function of PCNX1 Gene Knockout Cell Lines lies in their capacity to serve as models for assessing the gene's involvement in disease mechanisms, particularly in cancer biology and developmental disorders. By comparing the knockout cell lines with their wild-type counterparts, scientists can discern the pathways regulated by PCNX1, thus shedding light on its role in tumorigenesis or cellular maintenance. This can also facilitate drug discovery efforts, where researchers evaluate the effects of therapeutics on cells lacking specific gene function.
The scientific importance of these cell lines extends to various applications in both research and clinical environments. They can be utilized for high-throughput screening processes, validating targets for new pharmacological strategies, or understanding gene-environment interactions in complex diseases. Furthermore, the versatility of these cell lines makes them suitable for applying modern techniques such as RNA-sequencing or proteomics, providing comprehensive insights into cellular behavior.
One of the distinct advantages of our PCNX1 Gene Knockout Cell Lines over conventional models is their high specificity and reproducibility, which are critical for obtaining reliable data in gene function studies. Unlike traditional knockdown methods that often lead to incomplete inhibition, our knockout approach ensures a complete disruption of gene expression. This not only enhances the fidelity of experimental outcomes but also allows for more straightforward interpretation of results.
Researchers and clinicians will find immense value in our PCNX1 Gene Knockout Cell Lines, whether for basic research, drug development, or translational studies. Their capability to illuminate the roles of essential genes in health and disease offers a significant advantage in advancing knowledge and therapeutic strategies.
As an industry leader in the development of cutting-edge biological products, our company is committed to providing high-quality, reliable tools that empower the scientific community and drive innovation in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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