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PCMTD1 Knockout Cell Lines

Gene: PCMTD1

Official Full Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1provided by HGNC

Gene Summary: Enables ubiquitin-like ligase-substrate adaptor activity. Involved in protein ubiquitination. Part of Cul5-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30625 PCMTD1 Knockout cell line (HeLa) Human PCMTD1 1:3~1:6 Negative Online Inquiry
KO30626 PCMTD1 Knockout cell line (HCT 116) Human PCMTD1 1:2~1:4 Negative Online Inquiry
KO30627 PCMTD1 Knockout cell line (HEK293) Human PCMTD1 1:3~1:6 Negative Online Inquiry
KO30628 PCMTD1 Knockout cell line (A549) Human PCMTD1 1:3~1:4 Negative Online Inquiry

Background

PCMTD1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the PCMTD1 gene, which encodes for the protein involved in the post-translational modification of proteins via methylation. These cell lines serve as invaluable tools for investigating the role of PCMTD1 in various biological processes, including gene regulation, cellular metabolism, and stress responses. By removing the PCMTD1 gene, researchers can observe the resulting phenotypic and molecular changes, facilitating a deeper understanding of its functional significance in both normal and pathological states.

The primary mechanism of action associated with PCMTD1 is its involvement in the methylation of specific target proteins, which can modulate their activity, stability, and interactions with other cellular molecules. By studying PCMTD1 knockout cell lines, researchers can elucidate the downstream effects of this loss on cellular pathways, potentially linking dysregulation of PCMTD1 to diseases such as cancer or metabolic disorders.

The scientific importance of PCMTD1 Gene Knockout Cell Lines extends beyond basic research; they offer practical applications in drug discovery, biomarker identification, and therapeutic development. By providing a controlled environment to investigate gene function, these cell lines enable the identification of new drug targets and the validation of therapeutic strategies that might be impacted by PCMTD1 expression.

Among the unique advantages of our PCMTD1 Gene Knockout Cell Lines is their rigorously validated genetic profiling, ensuring the reliability and reproducibility of experimental results. Unlike alternative models that may exhibit background expression or other genetic variations, our knockout lines provide a clean genetic backdrop for experimental manipulation.

Researchers and clinicians will find these cell lines invaluable, not just for their potential to unlock new scientific insights, but also for their application in the development of innovative treatments. With each line, scientists can drive their research forward with a level of precision and clarity that paves the way for future breakthroughs.

Our company is dedicated to advancing biological research through the production of high-quality models like the PCMTD1 Gene Knockout Cell Lines. Our extensive expertise in genetic engineering and commitment to rigorous quality standards make us a trusted partner for researchers seeking to explore the complexities of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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