Gene: PCGF5
Official Full Name: polycomb group ring finger 5provided by HGNC
Gene Summary: Predicted to enable histone H2AK119 ubiquitin ligase activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus; centrosome; and nucleoplasm. Part of PcG protein complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24916 | PCGF5 Knockout cell line (HeLa) | Human | PCGF5 | 1:3~1:6 | Negative | Online Inquiry |
KO24917 | PCGF5 Knockout cell line (HCT 116) | Human | PCGF5 | 1:2~1:4 | Negative | Online Inquiry |
KO24918 | PCGF5 Knockout cell line (HEK293) | Human | PCGF5 | 1:3~1:6 | Negative | Online Inquiry |
KO24919 | PCGF5 Knockout cell line (A549) | Human | PCGF5 | 1:3~1:4 | Negative | Online Inquiry |
PCGF5 Gene Knockout Cell Lines are sophisticated biological tools generated through advanced genetic engineering techniques, specifically designed to ablate the expression of the PCGF5 gene, a crucial component involved in various cellular processes. By utilizing CRISPR-Cas9 technology, these cell lines have been meticulously crafted to provide a precise and stable genetic background, allowing for reliable studies into the function of the PCGF5 protein and its contributions to cellular behavior.
The primary mechanism behind the functionality of these knockout cell lines involves the targeted disruption of the PCGF5 gene, leading to the loss of function of the corresponding protein. This genetic alteration allows researchers to investigate the downstream effects on cellular pathways, gene expression profiles, and physiological responses, which are critical for understanding diseases such as cancer where PCGF5 may play a role.
Scientifically, PCGF5 Gene Knockout Cell Lines hold substantial importance in the domains of molecular biology and therapeutic research. They are invaluable in elucidating the biochemical mechanisms by which PCGF5 influences cellular dynamics, potentially leading to the identification of new therapeutic targets and the development of novel interventions. In clinical settings, these models can guide drug discovery and validation by offering insights into how the silencing of PCGF5 may affect cancer cell behavior or responses to treatment.
What sets PCGF5 Gene Knockout Cell Lines apart from alternative models is their rigorously validated performance and reproducibility, combined with the comprehensive characterization that accompanies every product. This ensures that researchers can confidently rely on the data derived from experiments conducted using these cell lines, minimizing variability and enhancing the robustness of findings.
For researchers and clinicians striving to push the boundaries of cellular and molecular understanding, the PCGF5 Gene Knockout Cell Lines represent an essential resource, enabling high-precision studies and rapid translation of findings into practical applications. At [Your Company Name], we specialize in providing high-quality biological products backed by extensive expertise in genomics and cell biology, ensuring that our users have access to reliable tools that enhance their research capabilities and clinical innovations.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.