Gene: PCDH7
Official Full Name: protocadherin 7provided by HGNC
Gene Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15314 | PCDH7 Knockout cell line (HeLa) | Human | PCDH7 | 1:3~1:6 | Negative | Online Inquiry |
KO15315 | PCDH7 Knockout cell line (HCT 116) | Human | PCDH7 | 1:2~1:4 | Negative | Online Inquiry |
KO15316 | PCDH7 Knockout cell line (HEK293) | Human | PCDH7 | 1:3~1:6 | Negative | Online Inquiry |
PCDH7 Gene Knockout Cell Lines are engineered cellular systems lacking the PCDH7 gene, a member of the protocadherin family implicated in crucial cellular processes such as cell-cell adhesion and neural differentiation. These knockout models are created through advanced gene editing techniques, including CRISPR/Cas9, allowing researchers to investigate the specific functions of PCDH7 in various biological contexts.
The primary mechanism of PCDH7 Gene Knockout Cell Lines involves the targeted disruption of the PCDH7 gene, facilitating the study of its role in cellular signaling pathways, tissue development, and disease processes. By observing the phenotypic changes that occur in the absence of PCDH7, researchers can elucidate its contributions to cell morphology, proliferation, and apoptosis, making these models invaluable for understanding the complexity of cellular interactions.
Scientifically, these cell lines hold significant importance in both research and clinical settings. They provide a platform for investigating the implications of PCDH7 in neurodegenerative diseases, cancer progression, and immune responses. By fostering a deeper comprehension of these pathways, researchers can identify potential therapeutic targets, ultimately leading to novel treatment strategies.
A key advantage of PCDH7 Gene Knockout Cell Lines is their specificity and reliability compared to alternative methods, such as siRNA-mediated knockdown, which may produce transient effects and off-target activity. Our knockout cell lines offer stable, long-term gene disruption, enabling reproducibility in experiments and validation of research findings.
For researchers and clinicians, the value of PCDH7 Gene Knockout Cell Lines lies in their ability to unlock new avenues of exploration in cellular biology and disease mechanisms, facilitating innovative breakthroughs in biotechnology and medicine. Our commitment to scientific excellence and cutting-edge genetic engineering positions us at the forefront of cellular tool development, ensuring that our products meet the highest standards for research and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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