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PAQR6 Knockout Cell Lines

Gene: PAQR6

Official Full Name: progestin and adipoQ receptor family member 6provided by HGNC

Gene Summary: Predicted to enable signaling receptor activity. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15362 PAQR6 Knockout cell line (HeLa) Human PAQR6 1:3~1:6 Negative Online Inquiry
KO15363 PAQR6 Knockout cell line (HCT 116) Human PAQR6 1:2~1:4 Negative Online Inquiry
KO15364 PAQR6 Knockout cell line (HEK293) Human PAQR6 1:3~1:6 Negative Online Inquiry
KO15365 PAQR6 Knockout cell line (A549) Human PAQR6 1:3~1:4 Negative Online Inquiry

Background

PAQR6 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the expression of the PAQR6 gene, a member of the progestin and adipoQ receptor family. These cell lines provide a vital tool for studying the biological roles of PAQR6 in various physiological processes and disease states. By utilizing these knockout models, researchers can dissect the molecular pathways mediated by PAQR6 and elucidate its function in cellular signaling, metabolism, and homeostasis.

The key functionality of PAQR6 Gene Knockout Cell Lines lies in their ability to facilitate loss-of-function studies. By comparing the expression profiles and phenotypic characteristics of these knockout lines with their wild-type counterparts, scientists can gain insights into the gene's involvement in processes such as adipogenesis, insulin signaling, and other metabolic pathways. The precise mechanisms by which PAQR6 modulates these processes are crucial for understanding disease mechanisms, particularly obesity, diabetes, and metabolic syndromes.

The scientific importance of these cell lines is underscored by their diverse applications in both basic research and clinical settings. In research, they serve as powerful models for drug testing, enabling the identification of novel therapeutic targets related to metabolic diseases. Clinically, understanding the role of PAQR6 may open avenues for the development of targeted therapies to manage or prevent conditions associated with its dysregulation.

What sets PAQR6 Gene Knockout Cell Lines apart from alternatives is their specificity and reliability. Developed using advanced CRISPR/Cas9 gene-editing technology, these cell lines ensure precise deletion of PAQR6 without off-target effects, making them a trusted choice for researchers requiring high fidelity in their experiments. Additionally, their robust performance in cell culture environments enhances their usability across various experimental conditions.

For researchers and clinicians dedicated to advancing the understanding of metabolic regulation and associated disorders, PAQR6 Gene Knockout Cell Lines present an invaluable resource. By allowing for detailed examination of gene function, they contribute significantly to the broader scientific community's efforts to unravel complex biological processes.

Our company is committed to providing high-quality, innovative biological products that empower researchers in their quest for knowledge and therapeutic breakthroughs. With a strong focus on precision and reliability, our offerings, including PAQR6 Gene Knockout Cell Lines, reflect our expertise in genetic modifications and cell line development.

Please note that all services are for research use only. Not intended for any clinical use.

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