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PALM3 Knockout Cell Lines

Gene: PALM3

Official Full Name: paralemmin 3provided by HGNC

Gene Summary: Predicted to enable ATP binding activity. Involved in Toll signaling pathway; negative regulation of cytokine-mediated signaling pathway; and response to lipopolysaccharide. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15380 PALM3 Knockout cell line (HCT 116) Human PALM3 1:2~1:4 Negative Online Inquiry
KO15381 PALM3 Knockout cell line (HEK293) Human PALM3 1:3~1:6 Negative Online Inquiry
KO15382 PALM3 Knockout cell line (A549) Human PALM3 1:3~1:4 Negative Online Inquiry

Background

PALM3 Gene Knockout Cell Lines are expertly engineered cell lines specifically designed to facilitate the study of the PALM3 gene’s function in various biological contexts. Gene knockout technology employs techniques such as CRISPR-Cas9 to create precise deletions of target genes, resulting in the complete absence of the PALM3 gene product. This allows researchers to investigate the effects of gene loss on cellular processes, signaling pathways, and disease models.

The key function of PALM3 Gene Knockout Cell Lines lies in their ability to provide a clear and consistent model for analyzing gene function and associated phenotypic changes. By removing the PALM3 gene, these cell lines permit the observation of alterations in cellular behavior, gene expression levels, and response to stimuli, offering insights into its role in cellular architecture and dynamics. This is crucial for understanding how PALM3 interacts within physiological and pathological processes, especially in cancers and neurodegenerative diseases.

Scientifically, PALM3 Gene Knockout Cell Lines have valuable applications in both basic research and clinical settings. They enable researchers to dissect the molecular mechanisms underpinning various disorders, paving the way for targeted therapies. Their utility extends to pharmacological studies where understanding gene function can guide drug development and optimization.

Compared to alternative models, such as transient knockdown systems, PALM3 Gene Knockout Cell Lines provide more stable and reproducible results due to the permanent gene modification. This stability is essential for long-term experiments and applications requiring consistent phenotypic expression.

For researchers, clinicians, and biotechnological firms, PALM3 Gene Knockout Cell Lines present an invaluable tool for advancing knowledge in molecular biology and therapeutic development. Their capacity to elucidate the role of PALM3 in disease mechanisms makes them an essential addition to any research toolkit.

Leveraging years of expertise in genetic engineering and cellular biology, our company is committed to providing high-quality research tools like PALM3 Gene Knockout Cell Lines, empowering the scientific community to achieve breakthroughs in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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