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PAAF1 Knockout Cell Lines

Gene: PAAF1

Official Full Name: proteasomal ATPase associated factor 1provided by HGNC

Gene Summary: This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26092 PAAF1 Knockout cell line (HeLa) Human PAAF1 1:3~1:6 Negative Online Inquiry
KO26093 PAAF1 Knockout cell line (HCT 116) Human PAAF1 1:2~1:4 Negative Online Inquiry
KO26094 PAAF1 Knockout cell line (HEK293) Human PAAF1 1:3~1:6 Negative Online Inquiry
KO26095 PAAF1 Knockout cell line (A549) Human PAAF1 1:3~1:4 Negative Online Inquiry

Background

PAAF1 Gene Knockout Cell Lines represent a pivotal advancement in genetic research, providing researchers with a powerful tool for studying the function of the PAAF1 gene and its associated pathways. These genetically modified cell lines are engineered to exhibit a complete knockout of the PAAF1 gene, effectively enabling the exploration of its role in various cellular processes, such as cell proliferation, differentiation, and response to stress. The mechanism of action hinges on precise gene-editing techniques, typically employing CRISPR-Cas9 technology, which allows for targeted and efficient disruption of the PAAF1 gene to elucidate its biological significance.

The scientific importance of PAAF1 Gene Knockout Cell Lines is substantial, as they enable researchers to interrogate the gene's contributions to critical physiological and pathological processes. In clinical research settings, these cell lines can be utilized to model diseases, such as cancer or metabolic disorders, where PAAF1 may play a role in disease progression. Furthermore, they can be instrumental in drug discovery programs, aiding in the identification of therapeutic targets and the assessment of drug efficacy in a controlled environment.

What sets our PAAF1 Gene Knockout Cell Lines apart from alternative products is their rigorously validated gene knockout efficiency and phenotypic characterization, ensuring that researchers can trust the data generated from these models. Additionally, the availability of various parental cell line backgrounds enhances versatility, catering to diverse experimental needs across multiple research disciplines.

For researchers and clinicians, the value of PAAF1 Gene Knockout Cell Lines is undeniable; they open novel avenues for understanding gene function, disease mechanisms, and therapeutic strategies. This pioneering resource empowers scientists to make groundbreaking discoveries with far-reaching implications in the fields of molecular biology and medicine.

Our company prides itself on its expertise in developing high-quality genetic models and cell lines, backed by years of research and a commitment to advancing scientific discovery. Through our dedication to innovation and quality, we provide unparalleled support to the global research community.

Please note that all services are for research use only. Not intended for any clinical use.

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