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OR5AL1 Knockout Cell Lines

Gene: OR5AL1

Official Full Name: olfactory receptor family 5 subfamily AL member 1 (gene/pseudogene)provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15484 OR5AL1 Knockout cell line (HeLa) Human OR5AL1 1:3~1:6 Negative Online Inquiry
KO15485 OR5AL1 Knockout cell line (HCT 116) Human OR5AL1 1:2~1:4 Negative Online Inquiry
KO15486 OR5AL1 Knockout cell line (HEK293) Human OR5AL1 1:3~1:6 Negative Online Inquiry
KO15487 OR5AL1 Knockout cell line (A549) Human OR5AL1 1:3~1:4 Negative Online Inquiry

Background

OR5AL1 Gene Knockout Cell Lines are specialized cell models engineered to lack the expression of the OR5AL1 gene, which is implicated in olfactory perception and plays a significant role in sensory signal transduction. Through the use of advanced CRISPR/Cas9 gene-editing technology, these cell lines allow researchers to study the fundamental biological processes affected by the loss of OR5AL1, providing insights into olfactory mechanisms and related disorders.

The key function of the OR5AL1 Gene Knockout Cell Lines is their ability to serve as a controlled environment for examining the physiological and biochemical consequences resulting from the absence of this receptor. Researchers can utilize these lines to investigate downstream signaling pathways, receptor interactions, and changes in cellular behavior, furthering our understanding of sensory biology.

From a scientific perspective, OR5AL1 Gene Knockout Cell Lines have profound implications in both basic research and clinical applications. They are essential for elucidating the functional role of the OR5AL1 receptor in various sensory and neurological conditions, paving the way for novel therapeutic strategies targeting olfactory dysfunction or related pathologies.

Compared to alternative methods such as pharmacological inhibition or overexpression systems, these knockout cell lines offer a more precise approach, eliminating confounding factors associated with non-specificity. This specificity enhances the reliability of experimental results and facilitates reproducibility, which is crucial for validation in scientific research.

For researchers, clinicians, and pharmacologists, the OR5AL1 Gene Knockout Cell Lines provide exceptional value by enabling targeted exploration of sensory pathways and potential drug discovery efforts. Their application can lead to breakthroughs not only in understanding olfactory biology but also in the broader context of neurobiology.

Our company specializes in developing high-quality biological products, and we take pride in offering innovative tools like the OR5AL1 Gene Knockout Cell Lines to empower scientific discovery and advance research in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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