Gene: OR51B6
Official Full Name: olfactory receptor family 51 subfamily B member 6provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15448 | OR51B6 Knockout cell line (HCT 116) | Human | OR51B6 | 1:2~1:4 | Negative | Online Inquiry |
OR51B6 Gene Knockout Cell Lines are advanced cellular models specifically engineered to inactivate the OR51B6 gene, which encodes a member of the olfactory receptor family implicated in various biological processes. These knockout cell lines facilitate the study of olfactory signaling pathways and their role in both physiological and pathological conditions. By removing the functional OR51B6 gene, researchers can investigate the gene's specific contributions to sensory perception, neurobiology, and potential implications in diseases, thereby providing a valuable tool for understanding complex biological mechanisms.
The key function of these knockout cell lines lies in their ability to elucidate the roles of OR51B6 in regulating olfactory signaling. This is achieved through the use of CRISPR-Cas9 technology, which ensures precise gene editing, enabling the deletion of the OR51B6 gene while maintaining the structural integrity of the surrounding genetic framework. The resultant cell lines allow researchers to analyze differences in signaling pathways, ligand binding, and downstream effects on cellular responses, offering insights into how disturbances in olfactory signaling may lead to various disorders.
The scientific importance of OR51B6 Gene Knockout Cell Lines extends to both basic research and clinical applications. Researchers can leverage these cell lines to explore the therapeutic potential of targeting olfactory receptors, and they can assess the impact of environmental factors on olfactory function. Furthermore, these models are ideal for drug discovery processes aimed at developing olfactory-related therapeutics, thus serving as a bridge between basic research and translational medicine.
Compared to alternative models, which may not accurately represent the nuances of the olfactory system, the OR51B6 knockout lines provide a more specific and targeted approach to studying olfactory receptors. This specificity offers distinct advantages for researchers looking for reliable data and reproducibility in their experiments.
For researchers and clinicians alike, the value of OR51B6 Gene Knockout Cell Lines is undeniable. They not only advance understanding of olfactory signaling but also contribute to the development of novel therapeutic strategies aimed at addressing sensory-related disorders. With our commitment to cutting-edge biotechnological advancements and our expertise in gene editing technologies, our company is positioned at the forefront of providing high-quality biological products that empower researchers and clinicians to push the boundaries of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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