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OR2B6 Knockout Cell Lines

Gene: OR2B6

Official Full Name: olfactory receptor family 2 subfamily B member 6provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28221 OR2B6 Knockout cell line (HeLa) Human OR2B6 1:3~1:6 Negative Online Inquiry

Background

OR2B6 Gene Knockout Cell Lines are a specialized biological tool designed to facilitate the study of the olfactory receptor gene OR2B6, which is implicated in the recognition of specific odorant molecules. These knockout cell lines are engineered to lack functional OR2B6 genes, allowing researchers to investigate the receptor's role in odor detection, signaling pathways, and potential implications in sensory biology.

The key function of these cell lines lies in their ability to provide a controlled environment for examining the consequences of OR2B6 gene deletion. By utilizing gene editing techniques, such as CRISPR-Cas9, these cells allow for precise analysis of receptor-mediated signaling mechanisms, downstream effects on cellular behavior, and any alterations in normal physiological responses to olfactory stimuli. Researchers can also employ these cell lines in high-throughput screening assays to identify potential pharmacological agents or to study the receptor's interactions with ligands.

The scientific significance of OR2B6 Gene Knockout Cell Lines extends to various applications in both basic research and clinical settings. They are particularly valuable in the fields of neuroscience and pharmacology, where understanding the intricate mechanisms of olfaction can lead to innovations in treating anosmia (loss of smell) and other olfactory disorders. Furthermore, these models can aid in drug discovery efforts targeting olfactory receptors, which play a crucial role in a range of human behaviors and biological processes.

When compared to traditional cell lines or models, OR2B6 Gene Knockout Cell Lines offer several distinct advantages. Their specificity eliminates background noise often encountered in non-targeted cell systems, ensuring more accurate results. Moreover, these knockout models can be readily manipulated for various experimental designs, making them versatile tools for researchers seeking to elucidate the complexities of olfactory signaling.

In summary, OR2B6 Gene Knockout Cell Lines provide a robust platform for advancing our understanding of olfactory receptor biology. They represent a valuable resource for researchers and clinicians alike, empowering them to unlock the mysteries of olfaction and its associated disorders. Our company has a proven track record of developing cutting-edge biological products, underscoring our commitment to supporting the scientific community with innovative solutions for research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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