Gene: ONECUT2
Official Full Name: one cut homeobox 2provided by HGNC
Gene Summary: This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33209 | ONECUT2 Knockout cell line (HeLa) | Human | ONECUT2 | 1:3~1:6 | Negative | Online Inquiry |
KO33210 | ONECUT2 Knockout cell line (HCT 116) | Human | ONECUT2 | 1:2~1:4 | Negative | Online Inquiry |
KO33211 | ONECUT2 Knockout cell line (HEK293) | Human | ONECUT2 | 1:3~1:6 | Negative | Online Inquiry |
ONECUT2 Gene Knockout Cell Lines are sophisticated biological tools designed for the targeted disruption of the ONECUT2 gene, which plays a critical role in various cellular processes, including differentiation, proliferation, and apoptosis. These cell lines utilize advanced CRISPR/Cas9 technology to create precise gene knockouts, allowing researchers to investigate the specific functions and pathogenic roles of ONECUT2 in both normal physiology and disease states.
The mechanism behind these knockout cell lines involves the introduction of a Cas9 endonuclease and guiding RNA specifically designed to bind to the ONECUT2 gene locus. This approach induces double-strand breaks in the DNA, leading to insertion or deletion mutations that effectively inactivate the gene. By utilizing these knockout models, scientists can elucidate the biological pathways influenced by ONECUT2, providing invaluable insights for both basic research and therapeutic development.
The scientific importance of ONECUT2 Gene Knockout Cell Lines is underscored by their applications in cancer research, developmental biology, and regenerative medicine. These models facilitate the exploration of how dysregulation of ONECUT2 contributes to malignancies and metabolic disorders, thus paving the way for novel therapeutic strategies.
One significant advantage of our ONECUT2 Gene Knockout Cell Lines lies in their robustness and reliability, as they are rigorously validated for consistent performance across experiments, ensuring reproducibility of results. Unlike traditional models, these knockout cell lines offer enhanced specificity and efficiency in gene editing, making them superior tools for any laboratory engaged in gene functional studies.
Researchers and clinicians seeking to deepen their understanding of ONECUT2 will find great value in these specialized cell lines. They provide a reliable platform for groundbreaking discoveries, ultimately contributing to advancements in personalized medicine and targeted therapies.
At our company, we pride ourselves on being at the forefront of genetic engineering, providing high-quality, validated biological products that empower scientists to achieve their research goals with confidence and precision.
Please note that all services are for research use only. Not intended for any clinical use.
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