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OLFM1 Knockout Cell Lines

Gene: OLFM1

Official Full Name: olfactomedin 1provided by HGNC

Gene Summary: This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31868 OLFM1 Knockout cell line (HeLa) Human OLFM1 1:3~1:6 Negative Online Inquiry
KO31869 OLFM1 Knockout cell line (HCT 116) Human OLFM1 1:2~1:4 Negative Online Inquiry
KO31870 OLFM1 Knockout cell line (HEK293) Human OLFM1 1:3~1:6 Negative Online Inquiry
KO31871 OLFM1 Knockout cell line (A549) Human OLFM1 1:3~1:4 Negative Online Inquiry

Background

OLFM1 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the biological functions of the OLFM1 gene in a controlled laboratory setting. This product involves targeted gene disruption, utilizing advanced CRISPR/Cas9 technology to create stable cell lines lacking the OLFM1 gene. The knockout of OLFM1 enables researchers to investigate its role in various biological processes, including cell proliferation, differentiation, and apoptosis, thereby providing insights into its contribution to various diseases, including cancer and neurological disorders.

The key mechanism behind OLFM1 knockout involves the precise editing of the genome to create a loss-of-function mutation. This targeted approach ensures that researchers can effectively analyze the phenotypic and molecular changes that occur in the absence of OLFM1, facilitating a deeper understanding of its functional pathways. This model not only accelerates discovery in functional genomics but also enables the validation of therapeutic targets linked to OLFM1.

The scientific importance of OLFM1 Gene Knockout Cell Lines extends beyond basic research; they have significant implications in drug development and personalized medicine. By mimicking the OLFM1 gene's inactivation found in certain patient populations, these cell lines can serve as important tools for evaluating potential therapeutic interventions and defining patient-specific responses to treatments.

Unique advantages of OLFM1 Gene Knockout Cell Lines include their robustness, reproducibility, and the purity of the knockout model, which surpasses conventional knockout models in specificity. Unlike other gene disruption methods, this product eliminates the risk of off-target effects, providing a reliable framework for studies requiring precise gene inactivation.

For researchers and clinicians delving into gene function, disease mechanisms, and therapeutic development, OLFM1 Gene Knockout Cell Lines are invaluable tools that enhance experimental design and elevate the quality of findings. As a leading provider of cutting-edge biological products, our company is dedicated to advancing research through innovative solutions tailored to meet the evolving demands of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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