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OGFRL1 Knockout Cell Lines

Gene: OGFRL1

Official Full Name: opioid growth factor receptor like 1provided by HGNC

Gene Summary: Predicted to enable opioid growth factor receptor activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15502 OGFRL1 Knockout cell line (HeLa) Human OGFRL1 1:3~1:6 Negative Online Inquiry
KO15503 OGFRL1 Knockout cell line (HCT 116) Human OGFRL1 1:2~1:4 Negative Online Inquiry
KO15504 OGFRL1 Knockout cell line (HEK293) Human OGFRL1 1:3~1:6 Negative Online Inquiry
KO15505 OGFRL1 Knockout cell line (A549) Human OGFRL1 1:3~1:4 Negative Online Inquiry

Background

OGFRL1 Gene Knockout Cell Lines are genetically modified cell lines that have been specifically designed to lack the expression of the OGF (Opioid Growth Factor) Receptor-Like 1 (OGFRL1) gene. These cell lines are valuable tools in molecular and cellular biology, enabling researchers to probe the functional roles of OGFRL1 in various biological processes, including cell growth, differentiation, and response to opioids. By knocking out this gene, researchers can investigate the pathways that are dependent on OGFRL1, providing insights into its potential contributions to tumorigenesis and therapeutic resistance.

The primary mechanism by which OGFRL1 Gene Knockout Cell Lines operate involves the disruption of the normal signaling pathways activated by the OGF-OGFr system. This interaction has been implicated in regulating cell proliferation and apoptosis. In knockout cell lines, the absence of OGFRL1 allows scientists to study compensatory mechanisms that may arise from the loss of this receptor, as well as the cellular response to opioids and other growth factors.

The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. In vitro studies utilizing OGFRL1 knockout models can potentially lead to new understandings of pain management, cancer biology, and regenerative medicine. By elucidating the pathways involved in OGFRL1 signaling, these cell lines can contribute to the identification of novel therapeutic targets and the development of innovative treatments for various diseases.

Compared to traditional wild-type cell lines, OGFRL1 Gene Knockout Cell Lines offer unique advantages that include precise control over receptor expression and the ability to create a more specific experimental context. This specificity reduces variability in experimental outcomes and enhances the reliability of results, making them indispensable for targeted studies.

For researchers and clinicians, the value of OGFRL1 Gene Knockout Cell Lines lies in their potential to drive discoveries in the areas of cancer research, pain modulation, and beyond. These cell lines can help bridge the gap between basic research and clinical applications, paving the way for new intervention strategies.

Our company is committed to providing high-quality biological products that empower researchers to conduct cutting-edge science. With expertise in genetic engineering and a focus on advancing biomedical research, we deliver solutions that enhance experimental accuracy and facilitate groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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