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ODF2L Knockout Cell Lines

Gene: ODF2L

Official Full Name: outer dense fiber of sperm tails 2 likeprovided by HGNC

Gene Summary: Involved in negative regulation of cilium assembly. Located in centriolar satellite and ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15523 ODF2L Knockout cell line (HeLa) Human ODF2L 1:3~1:6 Negative Online Inquiry
KO15524 ODF2L Knockout cell line (HCT 116) Human ODF2L 1:2~1:4 Negative Online Inquiry
KO15525 ODF2L Knockout cell line (HEK293) Human ODF2L 1:3~1:6 Negative Online Inquiry
KO15526 ODF2L Knockout cell line (A549) Human ODF2L 1:3~1:4 Negative Online Inquiry

Background

ODF2L Gene Knockout Cell Lines represent a cutting-edge resource in the field of genetic research, specifically designed to facilitate the study of the ODF2L gene's function in various biological processes. These cell lines have undergone precise genetic modifications to eliminate the expression of ODF2L, providing researchers with a powerful tool to elucidate the gene's role in cellular mechanisms, including sperm motility, ciliogenesis, and potential implications in fertility.

The key function of ODF2L Gene Knockout Cell Lines lies in their ability to mimic specific genetic conditions that can offer insights into disease mechanisms. By employing techniques such as CRISPR-Cas9 genome editing, these cell lines reliably exhibit a complete loss of ODF2L expression. This knockout model enables a plethora of experimental approaches, allowing scientists to analyze phenotypic changes, signaling pathways, and compensatory mechanisms that may occur in the absence of this gene.

In the context of scientific importance, the application of ODF2L knockout models in research extends to both fundamental biology and clinical implications. Investigators can leverage these cell lines to explore developmental biology, reveal targets for therapeutic intervention in fertility-related disorders, and enhance our understanding of ciliopathies. Such detailed exploration is paramount not only for academic research but also for the advancement of regenerative medicine.

Compared to existing alternatives, ODF2L Gene Knockout Cell Lines stand out due to their high specificity, reproducibility, and compatibility with a variety of cellular and molecular assays. While traditional knockdown methods may yield transient effects, our knockout lines provide stable and enduring genetic modifications that researchers can rely on for consistent results.

For researchers and clinicians alike, the value of the ODF2L Gene Knockout Cell Lines is clear: they provide a unique opportunity to uncover the intricate role of ODF2L in health and disease, potentially leading to breakthroughs in therapeutic strategies. Coupled with our commitment to excellence and innovation in biological product development, our expertise ensures that these cell lines are crafted under rigorous quality standards, promising reliability and versatility for pioneering research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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