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OARD1 Knockout Cell Lines

Gene: OARD1

Official Full Name: O-acyl-ADP-ribose deacylase 1provided by HGNC

Gene Summary: The protein encoded by this gene is a deacylase that can convert O-acetyl-ADP-ribose to ADP-ribose and acetate, O-propionyl-ADP-ribose to ADP-ribose and propionate, and O-butyryl-ADP-ribose to ADP-ribose and butyrate. The ADP-ribose product is able to inhibit these reactions through a competitive feedback loop. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27504 OARD1 Knockout cell line (HeLa) Human OARD1 1:3~1:6 Negative Online Inquiry
KO27505 OARD1 Knockout cell line (HCT 116) Human OARD1 1:2~1:4 Negative Online Inquiry
KO27506 OARD1 Knockout cell line (HEK293) Human OARD1 1:3~1:6 Negative Online Inquiry
KO27507 OARD1 Knockout cell line (A549) Human OARD1 1:3~1:4 Negative Online Inquiry

Background

OARD1 Gene Knockout Cell Lines are specifically engineered cellular models that enable researchers to study the biological functions of the OARD1 gene by effectively disrupting its expression. This targeted approach allows for the investigation of OARD1's role in various metabolic pathways, cellular responses to stress, and its implications in disease mechanisms, particularly in metabolic disorders and potential cancer research.

The knockout mechanism is facilitated through advanced gene-editing technologies, such as CRISPR/Cas9, which create specific deletions or mutations within the OARD1 gene, leading to a loss of function. As a result, these cell lines provide a valuable resource for understanding the downstream effects of OARD1 disruption, as they facilitate the assessment of alterations in cellular behavior, signaling pathways, and gene expression profiles.

The scientific importance of OARD1 Gene Knockout Cell Lines extends to both basic and applied research settings. In the laboratory, these models can be utilized to elucidate the precise role of OARD1 in cellular metabolism and its potential interactions with pharmacological agents. Moreover, they serve as vital tools in preclinical studies aimed at identifying new therapeutic targets for conditions linked to OARD1 dysfunction.

Compared to traditional overexpression models or non-targeted approaches, our OARD1 knockout cell lines offer clear advantages, including the ability to study physiological relevance without the confounding effects of gene overexpression. This specificity greatly enhances data validity and the reliability of experimental outcomes.

For researchers and clinicians, these knockout cell lines provide a critical advantage in translating laboratory findings into clinical insights, driving forward the understanding of disease mechanisms and the development of novel therapies. With years of specialized expertise in genetic engineering and cell line development, our company is committed to providing high-quality biological products that enhance research efficacy and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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