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NXT2 Knockout Cell Lines

Gene: NXT2

Official Full Name: nuclear transport factor 2 like export factor 2provided by HGNC

Gene Summary: The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15552 NXT2 Knockout cell line (HeLa) Human NXT2 1:3~1:6 Negative Online Inquiry
KO15553 NXT2 Knockout cell line (HCT 116) Human NXT2 1:2~1:4 Negative Online Inquiry
KO15554 NXT2 Knockout cell line (HEK293) Human NXT2 1:3~1:6 Negative Online Inquiry
KO15555 NXT2 Knockout cell line (A549) Human NXT2 1:3~1:4 Negative Online Inquiry

Background

NXT2 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the comprehensive study of the NXT2 gene and its associated biological pathways. These cell lines have undergone targeted gene disruption to eliminate the expression of the NXT2 gene, providing researchers with a powerful tool to investigate the functional role of NXT2 in cellular processes such as RNA transport, gene regulation, and overall cell metabolism.

The primary function of these knockout cell lines involves the attenuation of NXT2’s involvement in mRNA export from the nucleus to the cytoplasm, a crucial step in gene expression regulation. By utilizing CRISPR/Cas9 gene editing technology, these cell lines present an efficient approach to study the consequences of NXT2 loss on cell behavior, signaling pathways, and phenotypic changes. Researchers can observe alterations in cellular morphology, proliferation rates, and response to various stimuli, thus elucidating the gene's impact on cellular homeostasis and disease mechanisms.

The scientific importance of NXT2 Gene Knockout Cell Lines lies in their application across a variety of research domains, including molecular biology, oncology, and pharmacology. Understanding the role of NXT2 is vital for developing therapeutic strategies targeting diseases associated with aberrant mRNA processing and transport, including certain cancers and genetic disorders. These cell lines serve as a critical platform for drug discovery and efficacy studies, enabling high-throughput screening and validation of potential therapeutic agents.

One of the distinct advantages of our NXT2 Gene Knockout Cell Lines over traditional models is their specificity and accuracy in gene disruption, ensuring that any observed phenotypic changes can be directly attributed to the loss of NXT2 expression. Moreover, our lines are thoroughly validated for consistent performance and reproducibility, providing researchers with confidence in experimental results.

In summary, NXT2 Gene Knockout Cell Lines represent a valuable asset for those seeking to explore the intricate relations between gene function and cellular dynamics in both research and clinical settings. With our company’s extensive expertise in genetic engineering and commitment to scientific advancement, we provide researchers with top-quality biological products that empower innovative discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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