Gene: NUDT6
Official Full Name: nudix hydrolase 6provided by HGNC
Gene Summary: This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31143 | NUDT6 Knockout cell line (HeLa) | Human | NUDT6 | 1:3~1:6 | Negative | Online Inquiry |
KO31144 | NUDT6 Knockout cell line (HCT 116) | Human | NUDT6 | 1:2~1:4 | Negative | Online Inquiry |
KO31145 | NUDT6 Knockout cell line (HEK293) | Human | NUDT6 | 1:3~1:6 | Negative | Online Inquiry |
KO31146 | NUDT6 Knockout cell line (A549) | Human | NUDT6 | 1:3~1:4 | Negative | Online Inquiry |
NUDT6 Gene Knockout Cell Lines are a meticulously engineered group of cell lines in which the NUDT6 gene has been selectively inactivated or "knocked out". This innovative genetic modification facilitates the study of the NUDT6 protein's functional roles in cellular processes, particularly its involvement in RNA metabolism and cell signaling pathways. By disrupting the expression of NUDT6, researchers can observe resultant phenotypic changes that provide insights into the gene’s contributions to cellular functions and pathology.
The core mechanism of these knockout cell lines lies in the CRISPR-Cas9 technology employed for gene editing, which ensures high specificity and efficiency in targeting the NUDT6 gene. The resulting cell lines exhibit unique behavioral and biochemical characteristics, making them ideal models for investigations into genes' roles in cancer progression, drug resistance, and other disease states. Their utility extends to fundamental biology research as well as translational studies, where understanding NUDT6’s role could inform therapeutic strategies.
Compared to other knockout models, NUDT6 Gene Knockout Cell Lines offer distinct advantages such as robust reproducibility, streamlined validation processes, and compatibility with high-throughput screening applications. These cell lines serve as unparalleled tools for understanding complex genetic interactions and for drug discovery purposes, which are often hindered by the limitations of conventional models.
For researchers and clinicians aiming to advance our understanding of NUDT6 and its broader implications in human health, these knockout cell lines represent a valuable resource. Their precise genetic alteration allows for targeted studies that can enhance the development of innovative therapies.
Our company prides itself on its extensive expertise in cellular genetics and biotechnological innovations, ensuring that all products, including the NUDT6 Gene Knockout Cell Lines, are developed using the highest standards of quality and scientific rigor. We are dedicated to empowering researchers with the tools necessary to unlock new biological discoveries and improve clinical outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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