Gene: NUDT18
Official Full Name: nudix hydrolase 18provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates. [provided by RefSeq, Sep 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15583 | NUDT18 Knockout cell line (HeLa) | Human | NUDT18 | 1:3~1:6 | Negative | Online Inquiry |
KO15584 | NUDT18 Knockout cell line (HCT 116) | Human | NUDT18 | 1:2~1:4 | Negative | Online Inquiry |
KO15585 | NUDT18 Knockout cell line (HEK293) | Human | NUDT18 | 1:3~1:6 | Negative | Online Inquiry |
KO15586 | NUDT18 Knockout cell line (A549) | Human | NUDT18 | 1:3~1:4 | Negative | Online Inquiry |
NUDT18 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to inactivate the NUDT18 gene, which plays a critical role in cellular processes such as nucleotide metabolism and cellular stress response. By utilizing CRISPR-Cas9 technology, these cell lines enable researchers to study the loss-of-function effects of NUDT18 in various biological contexts, allowing for the exploration of its role in cancer biology, cellular aging, and metabolic disorders.
The NUDT18 gene encodes a protein involved in the hydrolysis of nucleotides, impacting the regulation of nucleotide pools within cells. Knocking out this gene creates a unique cellular environment where researchers can observe changes in metabolic pathways, cell cycle progression, and responses to genotoxic stress. These mechanisms provide essential insights that may lead to advancements in targeted therapies and novel treatment strategies.
In research and clinical settings, NUDT18 Knockout Cell Lines are invaluable for elucidating the gene's functional role, offering researchers a powerful tool to investigate gene interactions and potential therapeutic targets. Their utility greatly extends into drug discovery, genetic screening, and understanding the molecular basis of diseases linked to NUDT18 dysregulation.
Compared to other gene knockout models, NUDT18 Gene Knockout Cell Lines are produced using a highly efficient and precise gene-editing technique that ensures high specificity and low off-target effects. This precision minimizes variability in experimental results, offering researchers reliability in their findings.
For scientists and clinicians focused on understanding the complexities of cellular metabolism and stress responses, these knockout cell lines provide an indispensable resource. They offer enhanced experimental control and potential for innovative approaches in therapeutic development.
Our company’s expertise in gene editing and cell line generation, combined with unwavering commitment to quality, ensures that researchers have access to top-tier biological products that drive scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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