Gene: NUDT16
Official Full Name: nudix hydrolase 16provided by HGNC
Gene Summary: Enables several functions, including RNA binding activity; metal ion binding activity; and pyrophosphatase activity. Involved in RNA metabolic process and positive regulation of cell cycle process. Located in cytoplasm; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26552 | NUDT16 Knockout cell line (HeLa) | Human | NUDT16 | 1:3~1:6 | Negative | Online Inquiry |
KO26553 | NUDT16 Knockout cell line (HCT 116) | Human | NUDT16 | 1:2~1:4 | Negative | Online Inquiry |
KO26554 | NUDT16 Knockout cell line (HEK293) | Human | NUDT16 | 1:3~1:6 | Negative | Online Inquiry |
KO26555 | NUDT16 Knockout cell line (A549) | Human | NUDT16 | 1:3~1:4 | Negative | Online Inquiry |
NUDT16 Gene Knockout Cell Lines are a specialized biological product designed for advanced genetic research, specifically targeting the NUDT16 gene, which codes for a Nudix hydrolase involved in nucleotide metabolism. By effectively knocking out this gene, these cell lines enable researchers to analyze the functional consequences of NUDT16 deficiency, providing crucial insights into its role in cellular processes, DNA repair mechanisms, and the maintenance of genomic stability.
The primary function of NUDT16 knockouts lies in their ability to allow researchers to explore the biochemical pathways influenced by NUDT16, particularly its involvement in the hydrolysis of modified nucleotides. This mechanistic understanding is vital for elucidating the gene's impact on cellular proliferation, apoptosis, and overall homeostasis. Utilizing CRISPR/Cas9 technology, these knockout cell lines are meticulously engineered to ensure precise gene editing, which enhances reproducibility and reduces experimental variability.
The scientific importance of NUDT16 Gene Knockout Cell Lines extends to several applications, including cancer research, pharmacogenomics, and understanding metabolic disorders. In clinical settings, insights derived from these studies can lead to the development of new therapeutic strategies targeting nucleotide metabolism and its dysregulation in various diseases.
Compared to alternative genetic models, NUDT16 knockout cell lines offer the unique advantage of high specificity and reduced off-target effects, establishing a more reliable framework for experimental analysis. This specificity is instrumental for researchers focused on the nuanced roles of nucleotide metabolism in health and disease.
For researchers and clinicians, the value of these cell lines lies in their potential to bridge fundamental biological understanding with practical clinical applications. By leveraging NUDT16 knockout models, users can accelerate their research findings and potentially discover novel therapeutic targets.
Our company specializes in providing high-quality, validated genetic models and has extensive experience in gene editing technologies. We are committed to enhancing research capabilities, and our NUDT16 Gene Knockout Cell Lines represent a key offering that aligns with our dedication to advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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