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NUDT13 Knockout Cell Lines

Gene: NUDT13

Official Full Name: nudix hydrolase 13provided by HGNC

Gene Summary: Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NADH metabolic process and NADP catabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28565 NUDT13 Knockout cell line (HeLa) Human NUDT13 1:3~1:6 Negative Online Inquiry
KO28566 NUDT13 Knockout cell line (HCT 116) Human NUDT13 1:2~1:4 Negative Online Inquiry
KO28567 NUDT13 Knockout cell line (HEK293) Human NUDT13 1:3~1:6 Negative Online Inquiry
KO28568 NUDT13 Knockout cell line (A549) Human NUDT13 1:3~1:4 Negative Online Inquiry

Background

NUDT13 Gene Knockout Cell Lines represent a pioneering biological tool designed for the in-depth study of the NUDT13 gene and its associated cellular pathways. These genetically modified cell lines are created through advanced CRISPR-Cas9 technology, effectively rendering the NUDT13 gene non-functional. This allows researchers to observe the resultant phenotypic changes and elucidate the roles that NUDT13 plays in various biological processes, including DNA damage response and metabolic regulation.

The primary mechanism at play within these knockout cell lines is the disruption of the NUDT13 gene, which encodes for a hydrolytic enzyme involved in the metabolism of nucleotides. By knocking out this gene, researchers can investigate the downstream effects on cellular signaling, proliferation, and apoptosis, as well as gain insights into potential implications in cancer biology, metabolic disorders, and therapeutic response.

The scientific importance of NUDT13 Gene Knockout Cell Lines lies in their applications within both research and clinical settings. These cell lines are invaluable for studying the pathophysiology of diseases where NUDT13 may play a critical role, such as certain cancers, due to their capacity to model specific gene functions in vitro. Furthermore, these tools provide a platform for the testing of novel therapeutic strategies that target NUDT13-related pathways, thus accelerating the pace of discovery in drug development.

One notable advantage of NUDT13 Gene Knockout Cell Lines is their specificity and reliability as models compared to traditional methods, such as RNA interference. This specificity reduces the likelihood of off-target effects, allowing for clearer insights into gene-function relationships. Additionally, the ease of use and reproducibility of these lines makes them a superior choice for both high-throughput screening and elucidating complex cellular mechanisms.

For researchers and clinicians seeking to deepen their understanding of gene function and regulatory mechanisms, NUDT13 Gene Knockout Cell Lines offer unparalleled insights and innovative avenues for exploration. The unique potential of these cell lines paves the way for advancements in targeted therapies and personalized medicine. Our company, with a robust background in providing high-quality biological products and committed to advancing scientific knowledge, ensures that these products meet the highest standards of research integrity and efficacy.

Please note that all services are for research use only. Not intended for any clinical use.

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