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NTN1 Knockout Cell Lines

Gene: NTN1

Official Full Name: netrin 1provided by HGNC

Gene Summary: Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09925 NTN1 Knockout cell line (HCT 116) Human NTN1 1:2~1:4 Negative Online Inquiry
KO09926 NTN1 Knockout cell line (HEK293) Human NTN1 1:3~1:6 Negative Online Inquiry

Background

NTN1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the Netrin-1 (NTN1) gene, an essential component in various physiological processes, including neural development and cellular migration. These cell lines are crucial for studying the role of NTN1 in biological pathways, its contribution to neuronal guidance, and its implications in various diseases, such as cancer and neurological disorders.

The primary function of NTN1 Gene Knockout Cell Lines is to simulate the absence of Netrin-1, allowing researchers to investigate the downstream effects of NTN1 deficiency. This powerful tool enables exploration of cellular behaviors, including cell adhesion, chemotaxis, and apoptosis, through a loss-of-function approach. By examining these cell lines, scientists can elucidate the complex signaling pathways involved and their impact on normal cellular functions and disease pathology.

In research and clinical settings, NTN1 Gene Knockout Cell Lines play a pivotal role in understanding the underlying mechanisms of Netrin-1-related conditions, serving as valuable platforms for drug development and therapeutic interventions. They are particularly beneficial for researchers seeking to identify new therapeutic targets or disease biomarkers, enhancing the potential for translating laboratory findings into clinical applications.

One of the distinct advantages of our NTN1 Gene Knockout Cell Lines is their high specificity and reproducibility, which allows for reliable experimentation. Unlike alternative models that may exhibit variable gene expression, our knockout lines provide a consistent environment for studying the absence of NTN1. Furthermore, these cell lines are compatible with various assays, making them versatile tools across multiple research disciplines.

Investing in NTN1 Gene Knockout Cell Lines is highly beneficial for researchers and clinicians aiming to deepen their understanding of NTN1's biological functions and its role in disease. With our commitment to quality and innovation, our company offers unmatched expertise in producing reliable, tailored genetic models to support your research endeavors. We empower scientists to make impactful discoveries in the field of molecular biology and therapeutics.

Please note that all services are for research use only. Not intended for any clinical use.

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