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NT5DC3 Knockout Cell Lines

Gene: NT5DC3

Official Full Name: 5'-nucleotidase domain containing 3provided by HGNC

Gene Summary: Predicted to enable 5'-nucleotidase activity. Located in mitochondrion. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22407 NT5DC3 Knockout cell line (HeLa) Human NT5DC3 1:3~1:6 Negative Online Inquiry
KO22408 NT5DC3 Knockout cell line (HCT 116) Human NT5DC3 1:2~1:4 Negative Online Inquiry
KO22409 NT5DC3 Knockout cell line (HEK293) Human NT5DC3 1:3~1:6 Negative Online Inquiry
KO22410 NT5DC3 Knockout cell line (A549) Human NT5DC3 1:3~1:4 Negative Online Inquiry

Background

NT5DC3 Gene Knockout Cell Lines are advanced cellular models that have been genetically modified to disrupt the expression of the NT5DC3 gene, a critical component involved in nucleotide metabolism and signaling pathways. The knockout of this gene allows researchers to explore its role in various cellular processes, including cell differentiation, proliferation, and apoptosis, by utilizing the absence of the gene to delineate function.

The key mechanism by which NT5DC3 knockout cell lines operate involves the loss of enzymatic function attributed to NT5DC3, leading to altered intracellular levels of nucleotides and subsequently affecting downstream signaling pathways associated with cell survival and activity. Researchers can utilize these cell lines to gain insights into the molecular underpinnings of diseases such as cancer and neurological disorders, where aberrations in nucleotide metabolism may play a significant role.

The scientific importance of NT5DC3 gene knockout cell lines is substantial, particularly in the realm of functional genomics and drug development. By providing a platform to understand the consequences of NT5DC3 gene loss, these cell lines can facilitate the identification of potential therapeutic targets and biomarkers for clinical intervention. Moreover, they present an essential resource for screening drug candidates that may influence nucleotide metabolism or related pathways.

One distinctive advantage of our NT5DC3 knockout cell lines lies in their agility and precision compared to alternative models, such as conventional knockdown systems. The knockout approach eliminates concerns about residual gene activity, providing a more definitive tool for research. Furthermore, these cell lines are meticulously validated and characterized, ensuring reliability and reproducibility in outcomes.

For researchers and clinicians aiming to enhance their understanding of the complexities of cellular metabolism and related pathologies, NT5DC3 gene knockout cell lines represent an invaluable resource. They not only accelerate the pace of discovery but also streamline the pathway to translational research and therapeutic development. Our company prides itself on its expertise in providing high-quality biological products backed by solid scientific understanding, equipping scientists with the essential tools needed for cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

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