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NRIP2 Knockout Cell Lines

Gene: NRIP2

Official Full Name: nuclear receptor interacting protein 2provided by HGNC

Gene Summary: Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25390 NRIP2 Knockout cell line (HeLa) Human NRIP2 1:3~1:6 Negative Online Inquiry
KO25391 NRIP2 Knockout cell line (HCT 116) Human NRIP2 1:2~1:4 Negative Online Inquiry
KO25392 NRIP2 Knockout cell line (HEK293) Human NRIP2 1:3~1:6 Negative Online Inquiry

Background

NRIP2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the Nuclear Receptor Interacting Protein 2 (NRIP2) gene. This gene plays a crucial role in various signaling pathways, including those related to metabolic regulation and gene expression modulation. The knockout of NRIP2 allows researchers to study the resultant phenotypic changes and dissect its biological functions, aiding in the understanding of complex mechanisms underlying cellular processes.

The primary function of the NRIP2 knockout cell lines is to serve as a tool for elucidating the role of NRIP2 in various physiological and pathological contexts. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines exhibit a complete lack of NRIP2 expression, thereby providing a clear platform for cellular assays designed to explore gene function, signaling pathways, and molecular interactions. Researchers can investigate the impact on transcriptional activities, cellular proliferation, and responses to various stimuli, ultimately garnering insights into diseases such as cancer and metabolic disorders.

From a scientific perspective, NRIP2 Gene Knockout Cell Lines are invaluable in both research and clinical settings. They are particularly relevant for studies focusing on nuclear receptor activity, cellular metabolism, and the mechanistic dissection of gene regulatory networks. Their application extends to drug discovery, where understanding the specific pathways influenced by NRIP2 can lead to the identification of potential therapeutic targets.

The distinct advantage of NRIP2 Gene Knockout Cell Lines lies in their unparalleled specificity and functionality. Unlike traditional methods that may introduce off-target effects, our expertly validated cell lines ensure precise targeting, significantly reducing experimental variability. This precision enhances the reproducibility of results, making it easier for researchers to derive conclusive findings.

For researchers and clinicians, investing in NRIP2 Gene Knockout Cell Lines translates to obtaining a robust experimental platform that streamlines investigations into gene function and associated signaling pathways. With our commitment to quality and innovation, we leverage our extensive experience in genetic engineering to deliver products that meet the highest scientific standards, supporting the advancement of research and therapeutic developments.

Please note that all services are for research use only. Not intended for any clinical use.

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