Gene: NRIP1
Official Full Name: nuclear receptor interacting protein 1provided by HGNC
Gene Summary: Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03758 | NRIP1 Knockout cell line (HeLa) | Human | NRIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO03759 | NRIP1 Knockout cell line (HCT 116) | Human | NRIP1 | 1:2~1:4 | Negative | Online Inquiry |
KO03760 | NRIP1 Knockout cell line (HEK293) | Human | NRIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO03761 | NRIP1 Knockout cell line (A549) | Human | NRIP1 | 1:3~1:4 | Negative | Online Inquiry |
NRIP1 Gene Knockout Cell Lines are specialized cellular models specifically engineered to target and disrupt the NRIP1 gene, which encodes for the Nuclear Receptor Interacting Protein 1. This innovative product allows researchers to study the gene's role in various biological processes, including cell signaling pathways, transcriptional regulation, and its implications in diseases such as cancer and metabolic disorders.
These cell lines employ CRISPR-Cas9 technology, a revolutionary gene-editing tool that enables precise alteration of genomic DNA. By knocking out the NRIP1 gene, researchers can elucidate its functional significance, offering insights into how its absence affects cellular behavior, gene expression, and overall physiology. This process is critical for advancing our understanding of gene function in both normal and dysregulated states.
The scientific importance of NRIP1 Gene Knockout Cell Lines lies in their diverse applications in research settings. They serve as invaluable tools for drug discovery, enabling screening for therapeutic compounds that can modulate NRIP1-related pathways. Furthermore, these models are essential for experimental evaluations of gene therapy approaches aimed at restoring normal function or compensating for the loss of NRIP1 activity in disease contexts.
Compared to alternative cell lines, the NRIP1 knockouts provide unique advantages through their specificity and reproducibility, allowing for more reliable experimental outcomes. Additionally, they are adaptable to various research needs, facilitating high-throughput screening and mechanistic studies.
For researchers and clinicians, the value of NRIP1 Gene Knockout Cell Lines is evident in their ability to unlock new understanding about gene function and its implications in health and disease. This capability can lead to the identification of novel biomarkers and therapeutic targets, accelerating the translational process from bench to bedside.
Our company brings extensive expertise in the development and optimization of genetic models, ensuring that our NRIP1 Gene Knockout Cell Lines meet the highest standards of quality and performance. We are committed to supporting the research community with innovative biological products that drive scientific discovery and improve health outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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