Gene: NR5A2
Official Full Name: nuclear receptor subfamily 5 group A member 2provided by HGNC
Gene Summary: The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. [provided by RefSeq, Jun 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05300 | NR5A2 Knockout cell line (HCT 116) | Human | NR5A2 | 1:2~1:4 | Negative | Online Inquiry |
KO05301 | NR5A2 Knockout cell line (HEK293) | Human | NR5A2 | 1:3~1:6 | Negative | Online Inquiry |
KO05302 | NR5A2 Knockout cell line (A549) | Human | NR5A2 | 1:3~1:4 | Negative | Online Inquiry |
NR5A2 Gene Knockout Cell Lines are meticulously engineered cell lines in which the NR5A2 gene, known for its role in steroidogenesis and metabolism, has been inactivated to facilitate comprehensive scientific investigation. This powerful tool enables researchers to explore the gene's function in various physiological processes, including lipid metabolism, glucose homeostasis, and the regulation of adrenal and gonadal steroid production.
The primary function of these knockout cell lines is to serve as a platform for studying the gene's role in development and disease. By removing NR5A2, scientists can observe changes in cellular behavior, signaling pathways, and metabolic activities that would otherwise be masked. This allows for a deeper understanding of NR5A2's contributions to endocrine function and its implication in conditions such as obesity, diabetes, and hormone-related cancers.
The scientific importance of NR5A2 Gene Knockout Cell Lines cannot be overstated. They are invaluable for both basic research and translational studies. Researchers can utilize these lines to validate hypotheses related to NR5A2 function, conduct drug screening, and evaluate potential therapeutic targets in metabolic disorders. Thus, they play a critical role in advancing our understanding of complex biological systems and developing novel pharmacological therapies.
Compared to alternative models, such as wild-type cell lines or systems with partial gene silencing, NR5A2 Gene Knockout Cell Lines provide a definitive resource for elucidating the complete lack of NR5A2 function. This offers a clearer perspective for studies aimed at dissecting the intricate network of gene interactions and physiological effects that NR5A2 influences.
For researchers and clinicians, the value of NR5A2 Gene Knockout Cell Lines lies in their potential to streamline and enhance the research process, foster innovation, and ultimately improve patient outcomes through better-targeted therapies. The controlled genetic background of these lines ensures reproducibility and reliability in experimental results, making them an essential addition to any laboratory focused on metabolic and endocrine research.
At [Your Company Name], we pride ourselves on our commitment to quality and innovation in biological research tools. Our NR5A2 Gene Knockout Cell Lines exemplify our expertise in gene editing technology and dedication to supporting the scientific community in pioneering discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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