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NR2E1 Knockout Cell Lines

Gene: NR2E1

Official Full Name: nuclear receptor subfamily 2 group E member 1provided by HGNC

Gene Summary: The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05876 NR2E1 Knockout cell line (HEK293) Human NR2E1 1:3~1:6 Negative Online Inquiry

Background

NR2E1 Gene Knockout Cell Lines are genetically modified cell lines designed to study the functions and pathways associated with the NR2E1 gene, which encodes a nuclear hormone receptor critically involved in several developmental processes and disease states, including retinopathies and certain cancers. By generating a complete knockout of the NR2E1 gene, these cell lines provide a robust model to explore the gene's role in cellular differentiation, proliferation, and transcriptional regulation.

The key function of these knockout cell lines is their ability to facilitate in-depth investigations into the molecular mechanisms by which NR2E1 influences gene expression and cellular behavior. Research utilizing these cell lines can elucidate the downstream effects of NR2E1 loss, aiding in the identification of target genes and pathways that are altered in its absence. This knowledge is crucial for researchers aiming to develop therapies that could target NR2E1-related diseases or conditions.

The scientific importance of NR2E1 Gene Knockout Cell Lines extends to both basic research and potential therapeutic applications. In a clinical setting, understanding the precise role of NR2E1 could lead to innovative treatments for diseases where this gene plays a pivotal role. Moreover, these cell lines serve as a valuable tool for screening potential drug candidates that might modulate NR2E1's activity and influence related signaling pathways.

What sets our NR2E1 Gene Knockout Cell Lines apart from other models is their high specificity and reliability. Unlike standard cell lines, our products are rigorously validated, ensuring that any observed phenotypic changes are directly attributable to NR2E1 disruption. Additionally, they are available in multiple tissue backgrounds, allowing researchers to select the most appropriate model for their specific needs.

For researchers and clinicians, the NR2E1 Gene Knockout Cell Lines represent an excellent investment, providing a distinct advantage in the quest to unravel complex biological pathways and discover pioneering therapeutic interventions. Our commitment to high-quality, scientifically validated products, coupled with our extensive expertise in genetic engineering, underscores our dedication to advancing research in molecular biology and genetics.

Please note that all services are for research use only. Not intended for any clinical use.

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